Avril A B Robertson
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Explore the profile of Avril A B Robertson including associated specialties, affiliations and a list of published articles.
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72
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6484
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Recent Articles
1.
Chen R, Emming S, Cinnamon R, Cameron J, Schroder K, Kobe B, et al.
Org Biomol Chem
. 2024 Nov;
23(1):174-182.
PMID: 39526339
The NLRP3 inflammasome is implicated in the pathogenesis of a wide array of inflammatory diseases including cancer, type II diabetes, atherosclerosis, gout, and neurodegenerative disease. Research has shown that Bruton's...
2.
Jewell S, Nguyen T, Ascher D, Robertson A
Comput Struct Biotechnol J
. 2024 Oct;
23:3506-3513.
PMID: 39435340
Nucleotide-binding oligomerization domain, leucine rich repeat containing X1 (NLRX1) is a negative regulator of the nuclear factor kappa-light-chain-enhancer of activated B cells (NFκB) pathway, with a significant role in the...
3.
Wooff Y, Fernando N, Wong J, Dietrich C, Aggio-Bruce R, Chu-Tan J, et al.
Sci Rep
. 2024 Sep;
14(1):21585.
PMID: 39284853
No abstract available.
4.
Rahaman M, Thygesen S, Maxwell M, Kim H, Mudai P, Nanson J, et al.
J Enzyme Inhib Med Chem
. 2024 Feb;
39(1):2313055.
PMID: 38416868
Toll-like receptor (TLR) innate immunity signalling protects against pathogens, but excessive or prolonged signalling contributes to a range of inflammatory conditions. Structural information on the TLR cytoplasmic TIR (Toll/interleukin-1 receptor)...
5.
Horvat J, Kim R, Weaver N, Augood C, Brown A, Donovan C, et al.
Respir Res
. 2023 Dec;
24(1):303.
PMID: 38044426
Background: Increased airway NLRP3 inflammasome-mediated IL-1β responses may underpin severe neutrophilic asthma. However, whether increased inflammasome activation is unique to severe asthma, is a common feature of immune cells in...
6.
Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice
Overman J, Fontaine F, Moustaqil M, Mittal D, Sierecki E, Sacilotto N, et al.
Elife
. 2023 Aug;
12.
PMID: 37551662
No abstract available.
7.
Albornoz E, Gordon R, Kumar V, Robertson A, Schroder K, Woodruff T
Sci Transl Med
. 2023 May;
15(696):eadh0604.
PMID: 37196062
We have replicated our original finding of elevated cleaved caspase-1 in mouse brains and neuroprotection by an NLRP3 inflammasome inhibitor in two mouse models of Parkinson's disease.
8.
Prakash R, Vyawahare A, Sakla R, Kumari N, Kumar A, Ansari M, et al.
ACS Nano
. 2023 Apr;
17(9):8680-8693.
PMID: 37102996
Ischemia-reperfusion (I/R) injury is a disease process that affects several vital organs. There is widespread agreement that the NLRP3 inflammasome pathway plays a crucial role in the development of I/R...
9.
Wizrah M, Chua S, Luo Z, Manik M, Pan M, Whyte J, et al.
J Biol Chem
. 2022 Sep;
298(10):102453.
PMID: 36063996
The fungal pathogen Cryptococcus neoformans is a leading cause of meningoencephalitis in the immunocompromised. As current antifungal treatments are toxic to the host, costly, limited in their efficacy, and associated...
10.
Jing W, Lo Pilato J, Kay C, Feng S, Enosi Tuipulotu D, Mathur A, et al.
Sci Immunol
. 2022 May;
7(71):eabm1803.
PMID: 35594341
species are a group of Gram-positive bacteria that cause diseases in humans, such as food poisoning, botulism, and tetanus. Here, we analyzed 10 different species and identified that , a...