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Lucie Vankova

Explore the profile of Lucie Vankova including associated specialties, affiliations and a list of published articles. Areas
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Articles 6
Citations 43
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Recent Articles
1.
Mierzwicka J, Petrokova H, Raskova Kafkova L, Kosztyu P, cerny J, Kuchar M, et al.
J Transl Med . 2024 May; 22(1):426. PMID: 38711085
Background: Programmed cell death 1 (PD-1) belongs to immune checkpoint proteins ensuring negative regulation of the immune response. In non-small cell lung cancer (NSCLC), the sensitivity to treatment with anti-PD-1...
2.
Kuchar M, Kosztyu P, Daniel Liskova V, cerny J, Petrokova H, Vroblova E, et al.
Virulence . 2021 May; 12(1):1271-1287. PMID: 33993840
One of the proposed strategies for the development of a more efficient HIV-1 vaccine is based on the identification of proteins binding to a paratope of chosen broadly neutralizing antibody...
3.
Dostal J, Brynda J, Vankova L, Zia S, Pichova I, Heidingsfeld O, et al.
J Enzyme Inhib Med Chem . 2021 Apr; 36(1):914-921. PMID: 33843395
Pathogenic yeasts frequently cause infections in hospitals. Antifungal drugs lose effectiveness due to other species and resistance. New medications are thus required. Secreted aspartic protease of (Sapp1p) is a promising...
4.
Hlavnickova M, Kuchar M, Osicka R, Vankova L, Petrokova H, Maly M, et al.
Int J Mol Sci . 2018 Oct; 19(10). PMID: 30304852
Interleukin 17 (IL-17) and its cognate receptor A (IL-17RA) play a crucial role in Th17 cells-mediated pro-inflammatory pathway and pathogenesis of several autoimmune disorders including psoriasis. IL-17 is mainly produced...
5.
Skrlec K, Zadravec P, Hlavnickova M, Kuchar M, Vankova L, Petrokova H, et al.
Int J Mol Sci . 2018 Jul; 19(7). PMID: 29966384
IL-23-mediated Th-17 cell activation and stimulation of IL-17-driven pro-inflammatory axis has been associated with autoimmunity disorders such as Inflammatory Bowel Disease (IBD) or Crohn’s Disease (CD). Recently we developed a...
6.
Kuchar M, Vankova L, Petrokova H, cerny J, Osicka R, Pelak O, et al.
Proteins . 2014 Feb; 82(6):975-89. PMID: 24549990
Engineered combinatorial libraries derived from small protein scaffolds represent a powerful tool for generating novel binders with high affinity, required specificity and designed inhibitory function. This work was aimed to...