Lucie Roussel
Overview
Explore the profile of Lucie Roussel including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
4403
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Recent Articles
1.
Rubin T, Bernier S, Hoon Lim L, Salman M, Leung E, Mhanni A, et al.
Front Immunol
. 2025 Mar;
16:1557632.
PMID: 40061936
Background: Aicardi-Goutières syndrome (AGS) is a rare monogenic type I interferonopathy characterized by dysregulated inflammation and tissue damage that primarily affects the central nervous system. AGS is genetically diverse, with...
2.
Roussel L, Bernier S, Perez A, Sun Y, Angers I, Laneuville P, et al.
Br J Haematol
. 2024 Oct;
205(5):2089-2093.
PMID: 39364635
No abstract available.
3.
Bastard P, Gervais A, Taniguchi M, Saare L, Sarekannu K, Le Voyer T, et al.
J Exp Med
. 2024 Jan;
221(2).
PMID: 38175961
We found that 19 (10.4%) of 183 unvaccinated children hospitalized for COVID-19 pneumonia had autoantibodies (auto-Abs) neutralizing type I IFNs (IFN-α2 in 10 patients: IFN-α2 only in three, IFN-α2 plus...
4.
Roussel L, Pham-Huy A, Yu A, Venkateswaran S, Perez A, Bourdel G, et al.
J Clin Immunol
. 2023 Sep;
43(8):2011-2021.
PMID: 37695435
Autosomal recessive tyrosine kinase 2 (TYK2) deficiency is characterized by susceptibility to mycobacterial and viral infections. Here, we report a 4-year-old female with severe respiratory viral infections, EBV-driven Burkitt-like lymphoma,...
5.
Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs
Bastard P, Vazquez S, Liu J, Laurie M, Wang C, Gervais A, et al.
Sci Immunol
. 2022 Jul;
8(90):eabp8966.
PMID: 35857576
Life-threatening "breakthrough" cases of critical COVID-19 are attributed to poor or waning antibody (Ab) response to SARS-CoV-2 vaccines in individuals already at risk. Preexisting auto-Abs neutralizing type I IFNs underlie...
6.
Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, et al.
Proc Natl Acad Sci U S A
. 2022 May;
119(21):e2200413119.
PMID: 35576468
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection fatality rate (IFR) doubles with every 5 y of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found...
7.
Vinh D, Gouin J, Cruz-Santiago D, Canac-Marquis M, Bernier S, Bobeuf F, et al.
Lancet Healthy Longev
. 2022 Feb;
3(3):e166-e175.
PMID: 35224524
Background: The use of COVID-19 vaccines has been prioritised to protect the most vulnerable-notably, older people. Because of fluctuations in vaccine availability, strategies such as delayed second dose and heterologous...
8.
Manry J, Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, et al.
Res Sq
. 2022 Jan;
PMID: 35043109
SARS-CoV-2 infection fatality rate (IFR) doubles with every five years of age from childhood onward. Circulating autoantibodies neutralizing IFN-α, IFN-ω, and/or IFN-β are found in ~20% of deceased patients across...
9.
Al-Matar S, Sairam C, Roussel L, Langelier M, Vinh D
Lancet
. 2021 Dec;
398(10316):2101.
PMID: 34863351
No abstract available.
10.
Loo V, Roussel L, Bernier S, Perez A, Vinh D
J Clin Immunol
. 2021 Oct;
42(1):206-209.
PMID: 34694545
No abstract available.