Lucie Roussel
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Explore the profile of Lucie Roussel including associated specialties, affiliations and a list of published articles.
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38
Citations
4403
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Recent Articles
11.
Bastard P, Gervais A, Le Voyer T, Rosain J, Philippot Q, Manry J, et al.
Sci Immunol
. 2021 Aug;
6(62.
PMID: 34413139
Circulating autoantibodies (auto-Abs) neutralizing high concentrations (10 ng/mL, in plasma diluted 1 to 10) of IFN-α and/or -ω are found in about 10% of patients with critical COVID-19 pneumonia, but...
12.
Roussel L, Vinh D
Curr Opin Immunol
. 2021 Mar;
72:21-26.
PMID: 33756276
Autosomal recessive mutations in Inducible T Cell Costimulator Ligand (ICOSLG) result in a combined immunodeficiency syndrome of humans, saliently marked by recurrent respiratory tract infections and significant disease with DNA-based...
13.
Golizeh M, Winter K, Roussel L, Landekic M, Langelier M, Loo V, et al.
JCI Insight
. 2020 Nov;
6(1).
PMID: 33232301
Clostridioides difficile is a major cause of health care-associated diarrhea. Severity ranges from mild to life-threatening, but this variability remains poorly understood. Microbiologic diagnosis of C. difficile infection (CDI) is...
14.
Bastard P, Rosen L, Zhang Q, Michailidis E, Hoffmann H, Zhang Y, et al.
Science
. 2020 Sep;
370(6515).
PMID: 32972996
Interindividual clinical variability in the course of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is vast. We report that at least 101 of 987 patients with life-threatening coronavirus disease...
15.
Zhang Q, Bastard P, Liu Z, Le Pen J, Moncada-Velez M, Chen J, et al.
Science
. 2020 Sep;
370(6515).
PMID: 32972995
Clinical outcome upon infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ranges from silent infection to lethal coronavirus disease 2019 (COVID-19). We have found an enrichment in rare variants...
16.
Jiang H, Najmeh S, Martel G, MacFadden-Murphy E, Farias R, Savage P, et al.
Protein Cell
. 2020 Jan;
11(3):187-201.
PMID: 31956962
While emerging data suggest nucleotide oligomerization domain receptor 1 (NOD1), a cytoplasmic pattern recognition receptor, may play an important and complementary role in the immune response to bacterial infection, its...
17.
Roussel L, Landekic M, Golizeh M, Gavino C, Zhong M, Chen J, et al.
Med Sci (Paris)
. 2019 Sep;
35(8-9):625-628.
PMID: 31532372
No abstract available.
18.
Roussel L, Landekic M, Golizeh M, Gavino C, Zhong M, Chen J, et al.
J Exp Med
. 2018 Dec;
215(12):3151-3164.
PMID: 30498080
Primary immunodeficiencies represent naturally occurring experimental models to decipher human immunobiology. We report a patient with combined immunodeficiency, marked by recurrent respiratory tract and DNA-based viral infections, hypogammaglobulinemia, and panlymphopenia....
19.
Ruffin M, Roussel L, Maille E, Rousseau S, Brochiero E
Am J Physiol Lung Cell Mol Physiol
. 2018 Jan;
314(4):L635-L641.
PMID: 29351441
Cystic fibrosis patients exhibit chronic Pseudomonas aeruginosa respiratory infections and sustained proinflammatory state favoring lung tissue damage and remodeling, ultimately leading to respiratory failure. Loss of cystic fibrosis transmembrane conductance...
20.
Roussel L, LaFayette S, Nguyen D, Baglole C, Rousseau S
Front Cell Dev Biol
. 2017 Jan;
4:148.
PMID: 28066767
are gram-negative bacteria that frequently infect the lungs of cystic fibrosis (CF) patients. This bacterium is highly responsive to changes in its environment, resulting in the expression of a diverse...