Lucie Laplane
Overview
Explore the profile of Lucie Laplane including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
248
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Recent Articles
1.
Chin-Yee B, Laplane L, Sujobert P
Lancet Haematol
. 2025 Mar;
12(3):e224-e229.
PMID: 40044257
The growing use of measurable residual disease (MRD) assays across haematology-oncology creates an urgent need for clinicians and researchers to reflect on the biological and clinical rationale of this class...
2.
Marchand V, Laplane L, Valensi L, Plo I, Aglave M, Silvin A, et al.
iScience
. 2025 Jan;
28(1):111522.
PMID: 39811665
Elevated circulating levels of calprotectin (CAL), the S100A8/A9 heterodimer, are biomarkers of severe systemic inflammation. Here, we investigate the effects of CAL on early human hematopoiesis. CAL demonstrates limited impact...
3.
Hidaoui D, Porquet A, Chelbi R, Bohm M, Polyzou A, Alcazer V, et al.
Commun Biol
. 2024 Nov;
7(1):1555.
PMID: 39578583
Chronic myelomonocytic leukemia (CMML) is a severe myeloid malignancy affecting the elderly, for which therapeutic options are limited. DNA hypomethylating agents (HMAs) provide transient responses, failing to eradicate the malignant...
4.
CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia
Deschamps P, Wacheux M, Gosseye A, Morabito M, Pages A, Lyne A, et al.
J Clin Invest
. 2024 Nov;
134(22).
PMID: 39545419
Chronic myelomonocytic leukemia (CMML) is a severe myeloid malignancy with limited therapeutic options. Single-cell analysis of clonal architecture demonstrates early clonal dominance with few residual WT hematopoietic stem cells. Circulating...
5.
Laplane L, Maley C
Nat Rev Cancer
. 2024 Sep;
24(10):718-733.
PMID: 39256635
The clonal evolution model of cancer was developed in the 1950s-1970s and became central to cancer biology in the twenty-first century, largely through studies of cancer genetics. Although it has...
6.
Pare L, Bideau L, Baduel L, Dalle C, Benchouaia M, Schneider S, et al.
BMC Genomics
. 2023 Oct;
24(1):583.
PMID: 37784028
Background: Restorative regeneration, the capacity to reform a lost body part following amputation or injury, is an important and still poorly understood process in animals. Annelids, or segmented worms, show...
7.
Pradeu T, Daignan-Fornier B, Ewald A, Germain P, Okasha S, Plutynski A, et al.
Biol Rev Camb Philos Soc
. 2023 May;
98(5):1668-1686.
PMID: 37157910
Cancers rely on multiple, heterogeneous processes at different scales, pertaining to many biomedical fields. Therefore, understanding cancer is necessarily an interdisciplinary task that requires placing specialised experimental and clinical research...
8.
Willekens C, Laplane L, Dagher T, Benlabiod C, Papadopoulos N, Lacout C, et al.
Leukemia
. 2023 Apr;
37(6):1287-1297.
PMID: 37100881
Heterozygous mutation targeting proline 95 in Serine/Arginine-rich Splicing Factor 2 (SRSF2) is associated with V617F mutation in Janus Activated Kinase 2 (JAK2) in some myeloproliferative neoplasms (MPNs), most commonly primary...
9.
Sepich-Poore G, Guccione C, Laplane L, Pradeu T, Curtius K, Knight R
Bioessays
. 2022 Mar;
44(5):e2100252.
PMID: 35253252
The presence and role of microbes in human cancers has come full circle in the last century. Tumors are no longer considered aseptic, but implications for cancer biology and oncology...
10.
Chaintreuil P, Laplane L, Esnault F, Ghesquier V, Savy C, Furstoss N, et al.
Oncoimmunology
. 2022 Mar;
11(1):2015859.
PMID: 35251769
Macrophages are widely distributed innate immune cells that play an indispensable role in a variety of physiologic and pathologic processes, including organ development, host defense, acute and chronic inflammation, solid...