Nathalie Droin
Overview
Explore the profile of Nathalie Droin including associated specialties, affiliations and a list of published articles.
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Articles
113
Citations
4763
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Recent Articles
1.
Marchand V, Laplane L, Valensi L, Plo I, Aglave M, Silvin A, et al.
iScience
. 2025 Jan;
28(1):111522.
PMID: 39811665
Elevated circulating levels of calprotectin (CAL), the S100A8/A9 heterodimer, are biomarkers of severe systemic inflammation. Here, we investigate the effects of CAL on early human hematopoiesis. CAL demonstrates limited impact...
2.
Hidaoui D, Porquet A, Chelbi R, Bohm M, Polyzou A, Alcazer V, et al.
Commun Biol
. 2024 Nov;
7(1):1555.
PMID: 39578583
Chronic myelomonocytic leukemia (CMML) is a severe myeloid malignancy affecting the elderly, for which therapeutic options are limited. DNA hypomethylating agents (HMAs) provide transient responses, failing to eradicate the malignant...
3.
CXCL8 secreted by immature granulocytes inhibits WT hematopoiesis in chronic myelomonocytic leukemia
Deschamps P, Wacheux M, Gosseye A, Morabito M, Pages A, Lyne A, et al.
J Clin Invest
. 2024 Nov;
134(22).
PMID: 39545419
Chronic myelomonocytic leukemia (CMML) is a severe myeloid malignancy with limited therapeutic options. Single-cell analysis of clonal architecture demonstrates early clonal dominance with few residual WT hematopoietic stem cells. Circulating...
4.
Rabian F, Chevret S, Gruson B, Thepot S, Walter-Petrich A, Braun T, et al.
Leukemia
. 2024 Sep;
38(11):2510-2513.
PMID: 39266637
No abstract available.
5.
Ben-Crentsil N, Mohammed Ismail W, Balasis M, Newman H, Quintana A, Binder M, et al.
Cancer Discov
. 2024 Aug;
14(12):2509-2531.
PMID: 39189614
This work identifies MALAT1 as a requisite downstream effector of oncogenic feedforward inflammatory circuits necessary for the development of TET2-mutated CH and fulminant myeloid malignancy. We elucidate a novel mechanism...
6.
Rich J, Bennaroch M, Notel L, Patalakh P, Alberola J, Issa F, et al.
EMBO Mol Med
. 2024 Jul;
16(8):1840-1885.
PMID: 39009887
We have recently identified the uncharacterized ZNF555 protein as a component of a productive complex involved in the morbid function of the 4qA locus in facioscapulohumeral dystrophy. Subsequently named DiPRO1...
7.
Nguyen-Khac F, Baron M, Guieze R, Feugier P, Fayault A, Raynaud S, et al.
Br J Haematol
. 2024 Apr;
205(2):495-502.
PMID: 38654616
The potential prognostic influence of genetic aberrations on chronic lymphocytic leukaemia (CLL) can vary based on various factors, such as the immunoglobulin heavy variable (IGHV) status. We conducted an integrative...
8.
Rombaut D, Lefevre C, Rached T, Bondu S, Letessier A, Mangione R, et al.
Nat Commun
. 2024 Apr;
15(1):3016.
PMID: 38589367
Myelodysplastic syndromes (MDS) with mutated SF3B1 gene present features including a favourable outcome distinct from MDS with mutations in other splicing factor genes SRSF2 or U2AF1. Molecular bases of these...
9.
Ma H, Bizet M, Soares Da Costa C, Murisier F, de Bony E, Wang M, et al.
Mol Cell
. 2023 Dec;
83(23):4239-4254.e10.
PMID: 38065062
A common mRNA modification is 5-methylcytosine (mC), whose role in gene-transcript processing and cancer remains unclear. Here, we identify serine/arginine-rich splicing factor 2 (SRSF2) as a reader of mC and...
10.
Willekens C, Chahine C, Dragani M, Khalife-Hachem S, Bigenwald C, Rossignol J, et al.
EJHaem
. 2023 Aug;
4(3):823-826.
PMID: 37601857
No abstract available.