Lucie Laplane
Overview
Explore the profile of Lucie Laplane including associated specialties, affiliations and a list of published articles.
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23
Citations
248
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Recent Articles
11.
Duchmann M, Laplane L, Itzykson R
Cancers (Basel)
. 2021 Oct;
13(19).
PMID: 34638371
Acute myeloid leukemias (AML) results from the accumulation of genetic and epigenetic alterations, often in the context of an aging hematopoietic environment. The development of high-throughput sequencing-and more recently, of...
12.
Lambert J, Lloret-Fernandez C, Laplane L, Poole R, Jarriault S
Curr Top Dev Biol
. 2021 May;
144:111-159.
PMID: 33992151
How flexible are cell identities? This problem has fascinated developmental biologists for several centuries and can be traced back to Abraham Trembley's pioneering manipulations of Hydra to test its regeneration...
13.
Sevin M, Debeurme F, Laplane L, Badel S, Morabito M, Newman H, et al.
Blood
. 2021 Mar;
137(24):3390-3402.
PMID: 33690800
Mouse models of chronic myeloid malignancies suggest that targeting mature cells of the malignant clone disrupts feedback loops that promote disease expansion. Here, we show that in chronic myelomonocytic leukemia...
14.
Lyne A, Laplane L, Perie L
Blood
. 2021 Jan;
137(14):1862-1870.
PMID: 33512426
Clonal evolution, the process of expansion and diversification of mutated cells, plays an important role in cancer development, resistance, and relapse. Although clonal evolution is most often conceived of as...
15.
Beke A, Laplane L, Riviere J, Yang Q, Torres-Martin M, Dayris T, et al.
Haematologica
. 2019 May;
105(1):112-123.
PMID: 31048357
The functional diversity of cells that compose myeloid malignancies, i.e., the respective roles of genetic and epigenetic heterogeneity in this diversity, remains poorly understood. This question is addressed in chronic...
16.
Laplane L, Duluc D, Bikfalvi A, Larmonier N, Pradeu T
Int J Cancer
. 2019 Apr;
145(10):2611-2618.
PMID: 30989643
In contrast to the once dominant tumour-centric view of cancer, increasing attention is now being paid to the tumour microenvironment (TME), generally understood as the elements spatially located in the...
17.
Laplane L, Solary E
Elife
. 2019 Mar;
8.
PMID: 30864951
The characteristic properties of stem cells - notably their ability to self-renew and to differentiate - have meant that they have traditionally been viewed as distinct from most other types...
18.
Laplane L, Duluc D, Larmonier N, Pradeu T, Bikfalvi A
Trends Cancer
. 2018 Nov;
4(12):802-809.
PMID: 30470302
The notion of tumor microenvironment (TME) has been brought to the forefront of recent scientific literature on cancer. However, there is no consensus on how to define and spatially delineate...
19.
Laplane L, Solary E
Med Sci (Paris)
. 2017 Oct;
33(10):899-904.
PMID: 28994387
What is a stem cell? Is stemness an intrinsic or extrinsic property? What role does the microenvironment play in the stemness identity? We distinguish four identities for normal and cancerous...
20.