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Lucas E SantAnna

Explore the profile of Lucas E SantAnna including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Aldrete C, Call C, SantAnna L, Vlahos A, Pei J, Cong Q, et al.
Nat Chem Biol . 2025 Jan; PMID: 39814991
Synthetic circuits that regulate protein secretion in human cells could support cell-based therapies by enabling control over local environments. Although protein-level circuits enable such potential clinical applications, featuring orthogonality and...
2.
Aldrete C, Call C, SantAnna L, Vlahos A, Pei J, Cong Q, et al.
bioRxiv . 2024 Nov; PMID: 39484520
Synthetic circuits that regulate protein secretion in human cells could support cell-based therapies by enabling control over local environments. While protein-level circuits enable such potential clinical applications, featuring orthogonality and...
3.
Vu T, SantAnna L, Kamat N
Biomacromolecules . 2023 Mar; 24(4):1574-1584. PMID: 36943688
The addition of both cell-targeting moieties and polyethylene glycol (PEG) to nanoparticle (NP) drug delivery systems is a standard approach to improve the biodistribution, specificity, and uptake of therapeutic cargo....
4.
Vu T, Peruzzi J, SantAnna L, Roth E, Kamat N
Nano Lett . 2022 Mar; 22(7):2627-2634. PMID: 35298184
Ligand spatial presentation and density play important roles in signaling pathways mediated by cell receptors and are critical parameters when designing protein-conjugated therapeutic nanoparticles. Here, we harness lipid phase separation...