Justin A Peruzzi
Overview
Explore the profile of Justin A Peruzzi including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
11
Citations
106
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Peruzzi J, Gunnels T, Edelstein H, Lu P, Baker D, Leonard J, et al.
Nat Commun
. 2024 Jul;
15(1):5618.
PMID: 38965227
Naturally generated lipid nanoparticles termed extracellular vesicles (EVs) hold significant promise as engineerable therapeutic delivery vehicles. However, active loading of protein cargo into EVs in a manner that is useful...
2.
Peruzzi J, Steinkuhler J, Vu T, Gunnels T, Hu V, Lu P, et al.
Nat Commun
. 2024 Apr;
15(1):3162.
PMID: 38605024
The organization of membrane proteins between and within membrane-bound compartments is critical to cellular function. Yet we lack approaches to regulate this organization in a range of membrane-based materials, such...
3.
Steinkuhler J, Peruzzi J, Kruger A, Villasenor C, Jacobs M, Jewett M, et al.
ACS Synth Biol
. 2023 Dec;
13(1):129-140.
PMID: 38150067
Cell-free gene expression (CFE) systems are powerful tools for transcribing and translating genes outside of a living cell. Synthesis of membrane proteins is of particular interest, but their yield in...
4.
Peruzzi J, Galvez N, Kamat N
Proc Natl Acad Sci U S A
. 2023 May;
120(19):e2218610120.
PMID: 37126679
Cells use signal transduction across their membranes to sense and respond to a wide array of chemical and physical signals. Creating synthetic systems which can harness cellular signaling modalities promises...
5.
Peruzzi J, Vu T, Gunnels T, Kamat N
Small Methods
. 2023 Apr;
7(12):e2201718.
PMID: 37116099
The surface modification of membrane-based nanoparticles, such as liposomes, polymersomes, and lipid nanoparticles, with targeting molecules, such as binding proteins, is an important step in the design of therapeutic materials....
6.
Peruzzi J, Vu T, Kamat N
Trends Biotechnol
. 2023 Jan;
41(3):276-277.
PMID: 36646525
Morsut et al. reported a synthetic receptor system, based on the natural Notch receptor, with customizable input and output functions. Their work on advanced receptor design expands the reach of...
7.
Vu T, Peruzzi J, SantAnna L, Roth E, Kamat N
Nano Lett
. 2022 Mar;
22(7):2627-2634.
PMID: 35298184
Ligand spatial presentation and density play important roles in signaling pathways mediated by cell receptors and are critical parameters when designing protein-conjugated therapeutic nanoparticles. Here, we harness lipid phase separation...
8.
Hershewe J, Warfel K, Iyer S, Peruzzi J, Sullivan C, Roth E, et al.
Nat Commun
. 2021 Apr;
12(1):2363.
PMID: 33888690
Cell-free gene expression (CFE) systems from crude cellular extracts have attracted much attention for biomanufacturing and synthetic biology. However, activating membrane-dependent functionality of cell-derived vesicles in bacterial CFE systems has...
9.
Jacobs M, Faizi H, Peruzzi J, Vlahovska P, Kamat N
Biophys J
. 2021 Apr;
120(11):2317-2329.
PMID: 33887229
Polyunsaturated fatty acids (PUFAs) modify the activity of a wide range of membrane proteins and are increasingly hypothesized to modulate protein activity by indirectly altering membrane physical properties. Among the...
10.
Peruzzi J, Jacobs M, Vu T, Wang K, Kamat N
Angew Chem Int Ed Engl
. 2019 Oct;
58(51):18683-18690.
PMID: 31596992
Targeted vesicle fusion is a promising approach to selectively control interactions between vesicle compartments and would enable the initiation of biological reactions in complex aqueous environments. Here, we explore how...