Lisa Paschold
Overview
Explore the profile of Lisa Paschold including associated specialties, affiliations and a list of published articles.
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Articles
34
Citations
942
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Recent Articles
1.
Schultheiss C, Schmidt-Barbo P, Paschold L, Esperanzate C, Behn A, Mikolajczyk R, et al.
J Allergy Clin Immunol
. 2025 Feb;
PMID: 39924119
Background: Adenosine deaminase 2 deficiency (DADA2) is a genetic disorder caused by biallelic hypomorphic or loss-of-function mutations in the ADA2 gene, which encodes a protein deaminase regulating extracellular adenosine metabolism....
2.
Tintelnot J, Paschold L, Goekkurt E, Schultheiss C, Matschl U, Santos Cruz M, et al.
Cancer Immunol Res
. 2024 Nov;
13(2):200-209.
PMID: 39527097
Anti-PD-1, trastuzumab, and chemotherapy are used in the treatment of patients with advanced HER2-positive esophagogastric adenocarcinoma, but long-term survival remains limited. In this study, we report extended follow-up data from...
3.
Willscher E, Schultheiss C, Paschold L, Lea Schumann F, Schmidt-Barbo P, Thiele B, et al.
Haematologica
. 2024 Sep;
110(2):457-469.
PMID: 39219501
While T-cell lymphomas are classified as mature neoplasms, emerging evidence indicates that malignant transformation may occur at an earlier stage of T-cell maturation. In this study, we determined clonal architecture...
4.
Schultheiss C, Paschold L, Mohebiany A, Escher M, Kattimani Y, Muller M, et al.
Sci Adv
. 2024 Aug;
10(34):eadl3975.
PMID: 39167656
Genetic (A20) inactivation is a classical somatic lymphoma lesion and the genomic trait in haploinsufficiency of A20 (HA20). In a cohort of 34 patients with HA20, we show that heterozygous...
5.
Schultheiss C, Willscher E, Paschold L, Ackermann C, Escher M, Scholz R, et al.
Hepatol Commun
. 2024 Jul;
8(8).
PMID: 39082968
Background: Chronic HCV infection leads to a complex interplay with adaptive immune cells that may result in B cell dyscrasias like cryoglobulinemia or lymphoma. While direct-acting antiviral therapy has decreased...
6.
Thiele B, Stein A, Schultheiss C, Paschold L, Jonas H, Goekkurt E, et al.
Clin Colorectal Cancer
. 2024 Jul;
24(1):11-17.
PMID: 39003182
Background: Optimizing functional outcomes and securing long-term remissions are key goals in managing patients with locally advanced rectal cancer. In this proof-of-concept study, we set out to further optimize neoadjuvant...
7.
Schmidt-Barbo P, Kalweit G, Naouar M, Paschold L, Willscher E, Schultheiss C, et al.
PLoS Comput Biol
. 2024 Jul;
20(7):e1011570.
PMID: 38954728
The classification of B cell lymphomas-mainly based on light microscopy evaluation by a pathologist-requires many years of training. Since the B cell receptor (BCR) of the lymphoma clonotype and the...
8.
Fischer C, Willscher E, Paschold L, Gottschick C, Klee B, Diexer S, et al.
NPJ Vaccines
. 2024 Feb;
9(1):23.
PMID: 38316833
The rapid development of safe and effective vaccines helped to prevent severe disease courses after SARS-CoV-2 infection and to mitigate the progression of the COVID-19 pandemic. While there is evidence...
9.
Markl F, Schultheiss C, Ali M, Chen S, Zintchenko M, Egli L, et al.
Nat Commun
. 2024 Feb;
15(1):993.
PMID: 38307904
The concept of precision cell therapy targeting tumor-specific mutations is appealing but requires surface-exposed neoepitopes, which is a rarity in cancer. B cell receptors (BCR) of mature lymphoid malignancies are...
10.
Mohme M, Schultheiss C, Piffko A, Fitzek A, Paschold L, Thiele B, et al.
Clin Transl Immunology
. 2024 Feb;
13(2):e1487.
PMID: 38304555
Objectives: Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19). Although an acute SARS-CoV-2 infection mainly presents with respiratory illness, neurologic symptoms and sequelae are...