Edith Willscher
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Explore the profile of Edith Willscher including associated specialties, affiliations and a list of published articles.
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44
Citations
1431
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Recent Articles
1.
Thiele B, Schmidt-Barbo P, Schultheiss C, Willscher E, Weber T, Binder M
Nat Commun
. 2025 Jan;
16(1):1104.
PMID: 39881151
No abstract available.
2.
Engel K, Kulow V, Chernyakov D, Willscher E, Fahling M, Edemir B
FASEB J
. 2025 Jan;
39(2):e70352.
PMID: 39874047
Nuclear factor of activated T-cells 5 (NFAT5) is a transcription factor known for its role in osmotic stress adaptation in the renal inner medulla, due to the osmotic gradient that...
3.
Willscher E, Schultheiss C, Paschold L, Lea Schumann F, Schmidt-Barbo P, Thiele B, et al.
Haematologica
. 2024 Sep;
110(2):457-469.
PMID: 39219501
While T-cell lymphomas are classified as mature neoplasms, emerging evidence indicates that malignant transformation may occur at an earlier stage of T-cell maturation. In this study, we determined clonal architecture...
4.
Schultheiss C, Paschold L, Mohebiany A, Escher M, Kattimani Y, Muller M, et al.
Sci Adv
. 2024 Aug;
10(34):eadl3975.
PMID: 39167656
Genetic (A20) inactivation is a classical somatic lymphoma lesion and the genomic trait in haploinsufficiency of A20 (HA20). In a cohort of 34 patients with HA20, we show that heterozygous...
5.
Schultheiss C, Willscher E, Paschold L, Ackermann C, Escher M, Scholz R, et al.
Hepatol Commun
. 2024 Jul;
8(8).
PMID: 39082968
Background: Chronic HCV infection leads to a complex interplay with adaptive immune cells that may result in B cell dyscrasias like cryoglobulinemia or lymphoma. While direct-acting antiviral therapy has decreased...
6.
Schmidt-Barbo P, Kalweit G, Naouar M, Paschold L, Willscher E, Schultheiss C, et al.
PLoS Comput Biol
. 2024 Jul;
20(7):e1011570.
PMID: 38954728
The classification of B cell lymphomas-mainly based on light microscopy evaluation by a pathologist-requires many years of training. Since the B cell receptor (BCR) of the lymphoma clonotype and the...
7.
Fischer C, Willscher E, Paschold L, Gottschick C, Klee B, Diexer S, et al.
NPJ Vaccines
. 2024 Feb;
9(1):23.
PMID: 38316833
The rapid development of safe and effective vaccines helped to prevent severe disease courses after SARS-CoV-2 infection and to mitigate the progression of the COVID-19 pandemic. While there is evidence...
8.
Gross E, Hilger R, Lea Schumann F, Bauer M, Bouska A, Rohde C, et al.
Cancers (Basel)
. 2023 Jun;
15(11).
PMID: 37297005
T-cell lymphomas are heterogeneous and rare lymphatic malignancies with unfavorable prognosis. Consequently, new therapeutic strategies are needed. The enhancer of zeste homologue 2 (EZH2) is the catalytic subunit of the...
9.
Schultheiss C, Steinmann S, Willscher E, Paschold L, Lohse A, Binder M
Hepatol Commun
. 2023 Apr;
7(5).
PMID: 37102762
Background: Variant syndromes of autoimmune hepatitis (AIH) and primary biliary cholangitis (PBC) share diagnostic features of both entities, but their immunological underpinnings remain largely unexplored. Methods: We performed blood profiling...
10.
Uebel A, Kewitz-Hempel S, Willscher E, Gebhardt K, Sunderkotter C, Gerloff D
Int J Mol Sci
. 2023 Feb;
24(3).
PMID: 36768289
Activating BRAF mutations occurs in 50-60% of malignant melanomas. Although initially treatable, the development of resistance to BRAF-targeted therapies (BRAFi) is a major challenge and limits their efficacy. We have...