Christoph Schultheiss
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Explore the profile of Christoph Schultheiss including associated specialties, affiliations and a list of published articles.
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Articles
46
Citations
877
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Recent Articles
1.
Schultheiss C, Schmidt-Barbo P, Paschold L, Esperanzate C, Behn A, Mikolajczyk R, et al.
J Allergy Clin Immunol
. 2025 Feb;
PMID: 39924119
Background: Adenosine deaminase 2 deficiency (DADA2) is a genetic disorder caused by biallelic hypomorphic or loss-of-function mutations in the ADA2 gene, which encodes a protein deaminase regulating extracellular adenosine metabolism....
2.
Thiele B, Schmidt-Barbo P, Schultheiss C, Willscher E, Weber T, Binder M
Nat Commun
. 2025 Jan;
16(1):1104.
PMID: 39881151
No abstract available.
3.
Cardon A, Guinebretiere T, Dong C, Gil L, Ado S, Gavlovsky P, et al.
Nat Commun
. 2025 Jan;
16(1):1161.
PMID: 39880819
Autoimmune liver diseases (AILD) involve dysregulated CD4 T cell responses against liver self-antigens, but how these autoreactive T cells relate to liver tissue pathology remains unclear. Here we perform single-cell...
4.
Langer N, Weber M, Vieira B, Strzelczyk D, Wolf L, Pedroni A, et al.
Elife
. 2024 Nov;
13.
PMID: 39607424
Memory deficits are a hallmark of many different neurological and psychiatric conditions. The Rey-Osterrieth complex figure (ROCF) is the state-of-the-art assessment tool for neuropsychologists across the globe to assess the...
5.
Tintelnot J, Paschold L, Goekkurt E, Schultheiss C, Matschl U, Santos Cruz M, et al.
Cancer Immunol Res
. 2024 Nov;
13(2):200-209.
PMID: 39527097
Anti-PD-1, trastuzumab, and chemotherapy are used in the treatment of patients with advanced HER2-positive esophagogastric adenocarcinoma, but long-term survival remains limited. In this study, we report extended follow-up data from...
6.
Willscher E, Schultheiss C, Paschold L, Lea Schumann F, Schmidt-Barbo P, Thiele B, et al.
Haematologica
. 2024 Sep;
110(2):457-469.
PMID: 39219501
While T-cell lymphomas are classified as mature neoplasms, emerging evidence indicates that malignant transformation may occur at an earlier stage of T-cell maturation. In this study, we determined clonal architecture...
7.
Schultheiss C, Paschold L, Mohebiany A, Escher M, Kattimani Y, Muller M, et al.
Sci Adv
. 2024 Aug;
10(34):eadl3975.
PMID: 39167656
Genetic (A20) inactivation is a classical somatic lymphoma lesion and the genomic trait in haploinsufficiency of A20 (HA20). In a cohort of 34 patients with HA20, we show that heterozygous...
8.
Schultheiss C, Willscher E, Paschold L, Ackermann C, Escher M, Scholz R, et al.
Hepatol Commun
. 2024 Jul;
8(8).
PMID: 39082968
Background: Chronic HCV infection leads to a complex interplay with adaptive immune cells that may result in B cell dyscrasias like cryoglobulinemia or lymphoma. While direct-acting antiviral therapy has decreased...
9.
Thiele B, Stein A, Schultheiss C, Paschold L, Jonas H, Goekkurt E, et al.
Clin Colorectal Cancer
. 2024 Jul;
24(1):11-17.
PMID: 39003182
Background: Optimizing functional outcomes and securing long-term remissions are key goals in managing patients with locally advanced rectal cancer. In this proof-of-concept study, we set out to further optimize neoadjuvant...
10.
Schultheiss C, Buhlmann P, Yuan M
J Am Stat Assoc
. 2024 Jul;
119(546):1019-1031.
PMID: 38974187
We introduce a simple diagnostic test for assessing the overall or partial goodness of fit of a linear causal model with errors being independent of the covariates. In particular, we...