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Lisa K Denzin

Explore the profile of Lisa K Denzin including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 631
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Recent Articles
11.
Graves A, Virdis F, Morrison E, Alvaro-Benito M, Khan A, Freund C, et al.
J Immunol . 2020 Jul; 205(4):923-935. PMID: 32690655
HLA molecules of the MHC class II (MHCII) bind and present pathogen-derived peptides for CD4 T cell activation. Peptide loading of MHCII in the endosomes of cells is controlled by...
12.
Feng X, Lu H, Yue J, Shettigar M, Liu J, Denzin L, et al.
Int J Radiat Oncol Biol Phys . 2020 Apr; 107(4):779-792. PMID: 32259569
Purpose: Acquired hematopoietic failure is commonly caused by therapeutic and accidental exposure of the bone marrow (BM) to toxic agents. Efficient recovery from BM failure is dictated not only by...
13.
Darcy P, Denzin L, SantAngelo D
Sci Rep . 2020 Mar; 10(1):3897. PMID: 32127556
Co-expression of Yin Yang 1 (YY1) is required for the full function of the transcription factor, PLZF, which is essential for the development of natural killer T cell (NKT cell)...
14.
Newman J, Chesson C, Herzog N, Bommareddy P, Aspromonte S, Pepe R, et al.
Proc Natl Acad Sci U S A . 2020 Jan; 117(2):1119-1128. PMID: 31888983
Reprogramming the tumor microenvironment to increase immune-mediated responses is currently of intense interest. Patients with immune-infiltrated "hot" tumors demonstrate higher treatment response rates and improved survival. However, only the minority...
15.
Feng X, Lu H, Yue J, Schneider N, Liu J, Denzin L, et al.
DNA Repair (Amst) . 2019 Dec; 86:102754. PMID: 31794893
Radiation-induced lymphomagenesis results from a clonogenic lymphoid cell proliferation due to genetic alterations and immunological dysregulation. Mouse models had been successfully used to identify risk and protective factors for radiation-induced...
16.
Zhang S, Vieth J, Krzyzanowska A, Henry E, Denzin L, Siracusa M, et al.
J Immunol . 2019 Aug; 203(5):1230-1241. PMID: 31366712
Basophils are innate immune cells associated with type 2 immunity, allergic reactions, and host defense against parasite infections. In this study, we show that the transcription factor PLZF, which is...
17.
Darcy P, Jin K, Osorio L, Denzin L, SantAngelo D
J Immunol . 2019 Jun; 203(3):627-638. PMID: 31227579
The promyelocytic leukemia zinc-finger transcription factor (PLZF) is essential for nearly all of the unique, innate-like functions and characteristics of NKT cells. It is not known, however, if the activity...
18.
Denzin L, Khan A, Virdis F, Wilks J, Kane M, Beilinson H, et al.
Immunity . 2017 Aug; 47(2):310-322.e7. PMID: 28813660
Select humans and animals control persistent viral infections via adaptive immune responses that include production of neutralizing antibodies. The precise genetic basis for the control remains enigmatic. Here, we report...
19.
Vieth J, Das J, Ranaivoson F, Comoletti D, Denzin L, SantAngelo D
Nat Immunol . 2017 Jul; 18(8):951. PMID: 28722718
No abstract available.
20.
Vieth J, Das J, Ranaivoson F, Comoletti D, Denzin L, SantAngelo D
Nat Immunol . 2016 Nov; 18(1):36-44. PMID: 27869818
The interaction between the T cell antigen receptor (TCR) expressed by natural killer T cells (NKT cells) and the antigen-presenting molecule CD1d is distinct from interactions between the TCR and...