Jacques Thibodeau
Overview
Explore the profile of Jacques Thibodeau including associated specialties, affiliations and a list of published articles.
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Articles
49
Citations
955
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Recent Articles
1.
Balood M, Ahmadi M, Eichwald T, Ahmadi A, Majdoubi A, Roversi K, et al.
Nature
. 2022 Nov;
611(7935):405-412.
PMID: 36323780
Solid tumours are innervated by nerve fibres that arise from the autonomic and sensory peripheral nervous systems. Whether the neo-innervation of tumours by pain-initiating sensory neurons affects cancer immunosurveillance remains...
2.
Cloutier M, Fortin J, Thibodeau J
BMC Immunol
. 2021 Aug;
22(1):56.
PMID: 34384367
Background: Invariant chain (CD74, Ii) is a multifunctional protein expressed in antigen presenting cells. It assists the ER exit of various cargos and serves as a receptor for the macrophage...
3.
Crosson T, Wang J, Doyle B, Merrison H, Balood M, Parrin A, et al.
J Allergy Clin Immunol
. 2021 Jan;
147(6):2330-2342.
PMID: 33453289
Background: Lung nociceptor neurons amplify immune cell activity and mucus metaplasia in response to an inhaled allergen challenge in sensitized mice. Objective: We sought to identify the cellular mechanisms by...
4.
Majdoubi A, Lee J, Kishta O, Balood M, Moulefera M, Ishido S, et al.
Front Immunol
. 2020 Sep;
11:1953.
PMID: 32973799
Obesity is a major risk factor for the development of insulin resistance and type 2 diabetes. However, the mechanisms that trigger the underlying adipose tissues inflammation are not completely understood....
5.
Majdoubi A, Lee J, Balood M, Sabourin A, DeMontigny A, Kishta O, et al.
J Immunol
. 2019 Oct;
203(11):2887-2898.
PMID: 31659013
Dendritic cells (DCs) are critical players in skin homeostasis. A subset of mannose receptor (CD206)-expressing monocyte-derived DCs was found in skin, and their migratory counterpart is present in skin-draining lymph...
6.
Thibodeau J, Moulefera M, Balthazard R
Hum Immunol
. 2018 Oct;
80(1):15-31.
PMID: 30321632
Classical HLA class II molecules are highly polymorphic heterodimeric transmembrane proteins encoded by a polygenic cluster on chromosome 6. Polymorphic residues in the membrane-distal domains ensure that a large collection...
7.
Lee J, Jeong S, Kim S, Chalifour L, Yun T, Miah M, et al.
J Immunol
. 2018 Aug;
201(6):1784-1798.
PMID: 30097529
Ischemic myocardial injury results in sterile cardiac inflammation that leads to tissue repair, two processes controlled by mononuclear phagocytes. Despite global burden of cardiovascular diseases, we do not understand the...
8.
Letendre C, Auger J, Lemire P, Galbas T, Gottschalk M, Thibodeau J, et al.
Front Immunol
. 2018 Jun;
9:1199.
PMID: 29899744
is an important swine pathogen and emerging zoonotic agent. Encapsulated strains of modulate dendritic cell (DC) functions, leading to poorly activated CD4 T cells. However, the antigen presentation ability of...
9.
Kishta O, Sabourin A, Simon L, McGovern T, Raymond M, Galbas T, et al.
J Immunol Res
. 2018 Jun;
2018:3823910.
PMID: 29854835
Membrane-associated RING-CH-1 (March1) is a member of the March family of E3 ubiquitin ligases. March1 downregulates cell surface expression of MHC II and CD86 by targeting them to lysosomal degradation....
10.
Lemire P, Galbas T, Thibodeau J, Segura M
Front Microbiol
. 2017 Jul;
8:1196.
PMID: 28706510
Dendritic cells (DCs) and NK cells play a crucial role in the first phase of host defense against infections. Group B (GBS) and are encapsulated streptococci causing severe systemic inflammation,...