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Lisa Honold

Explore the profile of Lisa Honold including associated specialties, affiliations and a list of published articles. Areas
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Articles 14
Citations 587
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Recent Articles
1.
Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee I, et al.
Nat Cardiovasc Res . 2024 Feb; 2(12):1277-1290. PMID: 38344689
After myocardial infarction (MI), emergency hematopoiesis produces inflammatory myeloid cells that accelerate atherosclerosis and promote heart failure. Since the balance between glycolysis and mitochondrial metabolism regulates hematopoietic stem cell homeostasis,...
2.
Rohde D, Vandoorne K, Lee I, Grune J, Zhang S, McAlpine C, et al.
Nat Cardiovasc Res . 2022 Jun; 1(1):28-44. PMID: 35747128
Abnormal hematopoiesis advances cardiovascular disease by generating excess inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche regulates hematopoietic stem cell proliferation and hence the systemic...
3.
Honold L, Austrup M, Faust A, Paul Konken C, Schwegmann K, Zinnhardt B, et al.
Mol Imaging Biol . 2021 Nov; 24(3):434-443. PMID: 34750717
Introduction: Dysregulated activity of matrix metalloproteinases (MMPs) drives a variety of pathophysiological conditions. Non-invasive imaging of MMP activity in vivo promises diagnostic and prognostic value. However, current targeting strategies by...
4.
Frodermann V, Rohde D, Courties G, Severe N, Schloss M, Amatullah H, et al.
Nat Med . 2019 Nov; 25(11):1761-1771. PMID: 31700184
A sedentary lifestyle, chronic inflammation and leukocytosis increase atherosclerosis; however, it remains unclear whether regular physical activity influences leukocyte production. Here we show that voluntary running decreases hematopoietic activity in...
5.
Courties G, Frodermann V, Honold L, Zheng Y, Herisson F, Schloss M, et al.
Circ Res . 2019 Feb; 124(9):1372-1385. PMID: 30782088
Rationale: After a stroke, patients frequently experience altered systemic immunity resulting in peripheral immunosuppression and higher susceptibility to infections, which is at least partly attributed to lymphopenia. The mechanisms that...
6.
Vandoorne K, Rohde D, Kim H, Courties G, Wojtkiewicz G, Honold L, et al.
Circ Res . 2018 Jul; 123(4):415-427. PMID: 29980569
Rationale: Inflammatory stress induced by exposure to bacterial lipopolysaccharide causes hematopoietic stem cell expansion in the bone marrow niche, generating a cellular immune response. As an integral component of the...
7.
Zinnhardt B, Wiesmann M, Honold L, Barca C, Schafers M, Kiliaan A, et al.
Theranostics . 2018 May; 8(10):2603-2620. PMID: 29774062
Modulation of the inflammatory microenvironment after stroke opens a new avenue for the development of novel neurorestorative therapies in stroke. Understanding the spatio-temporal profile of (neuro-)inflammatory imaging biomarkers in detail...
8.
Gran S, Honold L, Fehler O, Zenker S, Eligehausen S, Kuhlmann M, et al.
Theranostics . 2018 May; 8(9):2407-2423. PMID: 29721088
Recruitment of leukocytes from the blood to sites of inflammation poses a promising target for new diagnostic and therapeutic approaches. We aimed to develop a novel method to non-invasively analyze...
9.
Honold L, Nahrendorf M
Circ Res . 2018 Jan; 122(1):113-127. PMID: 29301844
Macrophages are ubiquitous cells that reside in all major tissues. Counter to long-held beliefs, we now know that resident macrophages in many organs are seeded during embryonic development and self-renew...
10.
Zinnhardt B, Pigeon H, Theze B, Viel T, Wachsmuth L, Fricke I, et al.
Cancer Res . 2017 Feb; 77(8):1831-1841. PMID: 28137769
The tumor microenvironment is highly heterogeneous. For gliomas, the tumor-associated inflammatory response is pivotal to support growth and invasion. Factors of glioma growth, inflammation, and invasion, such as the translocator...