Sven Hermann
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Explore the profile of Sven Hermann including associated specialties, affiliations and a list of published articles.
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119
Citations
2100
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Recent Articles
1.
Landau F, Hermann S, Schelhaas S, Schafers M, Niemann S, Faust A
Nuklearmedizin
. 2024 Jul;
63(5):300-305.
PMID: 39084346
Aim: Bacterial infections are a clinical challenge, requiring fast and specific diagnosis to ensure effective treatment. Therefore, this project is dedicated to development of positron emission tomography (PET) radiotracers specifically...
2.
Hoffgen K, Dabel J, Konken C, Depke D, Hermann S, Dorner W, et al.
Nucl Med Biol
. 2024 Jul;
136-137:108937.
PMID: 38964257
Immunorecognition provides an excellent basis for targeted imaging techniques covering a wide range from basic research to diagnostics and from single cells to whole organisms. Fluorescence- or radioisotope-labeled antibodies, antibody...
3.
Prasad V, Wagner S, Keul P, Hermann S, Levkau B, Schafers M, et al.
Bioorg Med Chem
. 2024 Apr;
104:117697.
PMID: 38599005
Sphingosine-1-phosphate and its receptors (S1PRs) are involved in several diseases such as auto immunity, inflammation and cardiovascular disorders. The S1P analogue fingolimod (Gilenya®) is currently in use for the treatment...
4.
Nair Sailaja S, Maisuls I, Hepp A, Brunink D, Doltsinis N, Faust A, et al.
Int J Mol Sci
. 2024 Mar;
25(5).
PMID: 38473852
Metal phthalocyaninates and their higher homologues are recognized as deep-red luminophores emitting from their lowest excited singlet state. Herein, we report on the design, synthesis, and in-depth characterization of a...
5.
Margeta R, Schelhaas S, Hermann S, Schafers M, Niemann S, Faust A
Chem Commun (Camb)
. 2024 Feb;
60(26):3507-3510.
PMID: 38385843
For specific imaging of bacterial infections we aimed at targeting the exclusive bacterial iron transport system siderophore-based radiotracers. synthesis and radiolabeling yielded the salmochelin-based PET radiotracer [Ga]Ga-RMA693, which showed a...
6.
Roll W, Faust A, Hermann S, Schafers M
J Nucl Med
. 2023 Nov;
64(Suppl 2):59S-67S.
PMID: 37918846
Infections account for relevant morbidity and mortality, especially if the cardiovascular system is affected. Clinical manifestations are often unspecific, resulting in a challenging diagnostic work-up. The use of molecular imaging...
7.
Cufe J, Gierse F, Schafers K, Hermann S, Schafers M, Backhaus P, et al.
EJNMMI Res
. 2023 Sep;
13(1):86.
PMID: 37752319
Background: Kinetic modelling of dynamic PET typically requires knowledge of the arterial radiotracer concentration (arterial input function, AIF). Its accurate determination is very difficult in mice. AIF measurements in an...
8.
Tumor-Targeted Interleukin 2 Boosts the Anticancer Activity of FAP-Directed Radioligand Therapeutics
Galbiati A, Dorten P, Gilardoni E, Gierse F, Bocci M, Zana A, et al.
J Nucl Med
. 2023 Sep;
64(12):1934-1940.
PMID: 37734838
We studied the antitumor efficacy of a combination of Lu-labeled radioligand therapeutics targeting the fibroblast activation protein (FAP) (OncoFAP and BiOncoFAP) with the antibody-cytokine fusion protein L19-interleukin 2 (L19-IL2) providing...
9.
von Wulffen M, Luehrmann V, Robeck S, Russo A, Fischer-Riepe L, van den Bosch M, et al.
Cell Rep
. 2023 Aug;
42(8):113006.
PMID: 37610870
Immune-suppressive effects of myeloid-derived suppressor cells (MDSCs) are well characterized during anti-tumor immunity. The complex mechanisms promoting MDSC development and their regulatory effects during autoimmune diseases are less understood. We...
10.
Wolf M, Joseph R, Austermann J, Scharrnbeck-Davis C, Hermann S, Roth J, et al.
Biomedicines
. 2023 Mar;
11(3).
PMID: 36979814
Immune reactions are characterized by the rapid immigration of phagocytes into sites of inflammation. Meticulous regulation of these migratory processes is crucial for preventing uncontrolled and harmful phagocyte extravasation. S100A8/S100A9...