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David Rohde

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Articles 39
Citations 1247
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Recent Articles
1.
Grune J, Bajpai G, Ocak P, Kaufmann E, Mentkowski K, Pabel S, et al.
Circulation . 2024 Mar; 150(1):49-61. PMID: 38506045
Background: Viral infections can cause acute respiratory distress syndrome (ARDS), systemic inflammation, and secondary cardiovascular complications. Lung macrophage subsets change during ARDS, but the role of heart macrophages in cardiac...
2.
Zhang S, Paccalet A, Rohde D, Cremer S, Hulsmans M, Lee I, et al.
Nat Cardiovasc Res . 2024 Feb; 2(12):1277-1290. PMID: 38344689
After myocardial infarction (MI), emergency hematopoiesis produces inflammatory myeloid cells that accelerate atherosclerosis and promote heart failure. Since the balance between glycolysis and mitochondrial metabolism regulates hematopoietic stem cell homeostasis,...
3.
Hulsmans M, Schloss M, Lee I, Bapat A, Iwamoto Y, Vinegoni C, et al.
Science . 2023 Jul; 381(6654):231-239. PMID: 37440641
Atrial fibrillation disrupts contraction of the atria, leading to stroke and heart failure. We deciphered how immune and stromal cells contribute to atrial fibrillation. Single-cell transcriptomes from human atria documented...
4.
Lauer A, Speroni S, Choi M, Da X, Duncan C, McCarthy S, et al.
Nat Commun . 2023 Apr; 14(1):1900. PMID: 37019892
Blood-brain barrier disruption marks the onset of cerebral adrenoleukodystrophy (CALD), a devastating cerebral demyelinating disease caused by loss of ABCD1 gene function. The underlying mechanism are not well understood, but...
5.
Grune J, Lewis A, Yamazoe M, Hulsmans M, Rohde D, Xiao L, et al.
Nat Cardiovasc Res . 2022 Aug; 1(7):649-664. PMID: 36034743
Sudden cardiac death, arising from abnormal electrical conduction, occurs frequently in patients with coronary heart disease. Myocardial ischemia simultaneously induces arrhythmia and massive myocardial leukocyte changes. In this study, we...
6.
Rohde D, Vandoorne K, Lee I, Grune J, Zhang S, McAlpine C, et al.
Nat Cardiovasc Res . 2022 Jun; 1(1):28-44. PMID: 35747128
Abnormal hematopoiesis advances cardiovascular disease by generating excess inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche regulates hematopoietic stem cell proliferation and hence the systemic...
7.
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al.
Nat Immunol . 2022 Jun; 23(8):1285. PMID: 35705799
No abstract available.
8.
Pulous F, Cruz-Hernandez J, Yang C, Kaya Z, Paccalet A, Wojtkiewicz G, et al.
Nat Neurosci . 2022 May; 25(5):567-576. PMID: 35501382
Interactions between the immune and central nervous systems strongly influence brain health. Although the blood-brain barrier restricts this crosstalk, we now know that meningeal gateways through brain border tissues facilitate...
9.
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al.
Nat Immunol . 2022 Mar; 23(4):605-618. PMID: 35352063
Autonomic nerves control organ function through the sympathetic and parasympathetic branches, which have opposite effects. In the bone marrow, sympathetic (adrenergic) nerves promote hematopoiesis; however, how parasympathetic (cholinergic) signals modulate...
10.
Rohde D, Nahrendorf M
Cardiovasc Res . 2021 Mar; 117(4):993-994. PMID: 33693568
No abstract available.