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Gabriel Courties

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Articles 48
Citations 4933
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Recent Articles
1.
Rohde D, Vandoorne K, Lee I, Grune J, Zhang S, McAlpine C, et al.
Nat Cardiovasc Res . 2022 Jun; 1(1):28-44. PMID: 35747128
Abnormal hematopoiesis advances cardiovascular disease by generating excess inflammatory leukocytes that attack the arteries and the heart. The bone marrow niche regulates hematopoietic stem cell proliferation and hence the systemic...
2.
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al.
Nat Immunol . 2022 Jun; 23(8):1285. PMID: 35705799
No abstract available.
3.
Schloss M, Hulsmans M, Rohde D, Lee I, Severe N, Foy B, et al.
Nat Immunol . 2022 Mar; 23(4):605-618. PMID: 35352063
Autonomic nerves control organ function through the sympathetic and parasympathetic branches, which have opposite effects. In the bone marrow, sympathetic (adrenergic) nerves promote hematopoiesis; however, how parasympathetic (cholinergic) signals modulate...
4.
Hannemann N, Apparailly F, Courties G
Trends Immunol . 2021 Apr; 42(5):368-371. PMID: 33832864
Like other tissues, joints contain resident macrophages, and their diversity is only beginning to be characterized. Based on the highlights of recent studies, we discuss where current challenges lie and...
5.
Boutet M, Courties G, Nerviani A, Le Goff B, Apparailly F, Pitzalis C, et al.
Autoimmun Rev . 2021 Jan; 20(3):102758. PMID: 33476818
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease affecting joints and causing progressive damage and disability. Macrophages are of critical importance in the initiation and perpetuation of synovitis in...
6.
Panizzi P, Krohn-Grimberghe M, Keliher E, Ye Y, Grune J, Frodermann V, et al.
Sci Transl Med . 2020 Nov; 12(568). PMID: 33148623
Acute bacterial endocarditis is a rapid, difficult to manage, and frequently lethal disease. Potent antibiotics often cannot efficiently kill that colonizes the heart's valves. relies on virulence factors to evade...
7.
Hannemann N, Apparailly F, Courties G
Joint Bone Spine . 2020 Nov; 88(1):105091. PMID: 33130232
Rheumatoid arthritis (RA) is a prototypic autoimmune disease that primarily affects joints. Clinical studies and animal models evidenced that mononuclear phagocytes including monocytes and macrophages are crucial to RA pathogenesis,...
8.
Krohn-Grimberghe M, Mitchell M, Schloss M, Khan O, Courties G, Guimaraes P, et al.
Nat Biomed Eng . 2020 Oct; 4(11):1076-1089. PMID: 33020600
Bone-marrow endothelial cells in the haematopoietic stem-cell niche form a network of blood vessels that regulates blood-cell traffic as well as the maintenance and function of haematopoietic stem and progenitor...
9.
Vinegoni C, Fumene Feruglio P, Courties G, Schmidt S, Hulsmans M, Lee S, et al.
Sci Rep . 2020 Mar; 10(1):5632. PMID: 32221334
Understanding complex biological systems requires the system-wide characterization of cellular and molecular features. Recent advances in optical imaging technologies and chemical tissue clearing have facilitated the acquisition of whole-organ imaging...
10.
Hoyer F, Naxerova K, Schloss M, Hulsmans M, Nair A, Dutta P, et al.
Immunity . 2019 Nov; 51(5):899-914.e7. PMID: 31732166
Myocardial infarction, stroke, and sepsis trigger systemic inflammation and organism-wide complications that are difficult to manage. Here, we examined the contribution of macrophages residing in vital organs to the systemic...