Lisa D Urness
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Explore the profile of Lisa D Urness including associated specialties, affiliations and a list of published articles.
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16
Citations
820
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Recent Articles
1.
Urness L, Wang X, Li C, Quadros R, Harms D, Gurumurthy C, et al.
Development
. 2020 Jun;
147(13).
PMID: 32541002
Pan-otic CRE drivers enable gene regulation throughout the otic placode lineage, comprising the inner ear epithelium and neurons. However, intersection of extra-otic gene-of-interest expression with the CRE lineage can compromise...
2.
Urness L, Wang X, Doan H, Shumway N, Noyes C, Gutierrez-Magana E, et al.
Development
. 2018 Dec;
145(24).
PMID: 30504125
Morphogenesis of the inner ear epithelium requires coordinated deployment of several signaling pathways, and disruptions cause abnormalities of hearing and/or balance. The FGFR2b ligands FGF3 and FGF10 are expressed throughout...
3.
Quadros R, Miura H, Harms D, Akatsuka H, Sato T, Aida T, et al.
Genome Biol
. 2017 May;
18(1):92.
PMID: 28511701
Background: Conditional knockout mice and transgenic mice expressing recombinases, reporters, and inducible transcriptional activators are key for many genetic studies and comprise over 90% of mouse models created. Conditional knockout...
4.
Urness L, Wang X, Shibata S, Ohyama T, Mansour S
Dev Biol
. 2015 Jan;
400(1):59-71.
PMID: 25624266
The vertebrate inner ear is a morphologically complex sensory organ comprised of two compartments, the dorsal vestibular apparatus and the ventral cochlear duct, required for motion and sound detection, respectively....
5.
Mansour S, Li C, Urness L
Genes Dev
. 2013 Oct;
27(21):2320-31.
PMID: 24145799
The stereotyped arrangement of cochlear sensory and supporting cells is critical for auditory function. Our previous studies showed that Muenke syndrome model mice (Fgfr3P244R/+) have hearing loss associated with a...
6.
Urness L, Bleyl S, Wright T, Moon A, Mansour S
Dev Biol
. 2011 Jun;
356(2):383-97.
PMID: 21664901
Heart development requires contributions from, and coordinated signaling interactions between, several cell populations, including splanchnic and pharyngeal mesoderm, postotic neural crest and the proepicardium. Here we report that Fgf3 and...
7.
Wythe J, Jurynec M, Urness L, Jones C, Sabeh M, Werdich A, et al.
Dis Model Mech
. 2011 Jun;
4(5):607-21.
PMID: 21628396
The vertebrate heart is one of the first organs to form, and its early function and morphogenesis are crucial for continued embryonic development. Here we analyze the effects of loss...
8.
Urness L, Paxton C, Wang X, Schoenwolf G, Mansour S
Dev Biol
. 2010 Feb;
340(2):595-604.
PMID: 20171206
The inner ear epithelium, with its complex array of sensory, non-sensory, and neuronal cell types necessary for hearing and balance, is derived from a thickened patch of head ectoderm called...
9.
Hatch E, Urness L, Mansour S
Dev Dyn
. 2008 Sep;
238(2):358-66.
PMID: 18773497
Fibroblast growth factors play important roles in inner ear development. Previous studies showed that mouse Fgf16 is expressed asymmetrically during the otic cup and vesicle stages of development, suggesting roles...
10.
Urness L, Li C, Wang X, Mansour S
Dev Dyn
. 2007 Dec;
237(1):163-9.
PMID: 18058922
The levels of fibroblast growth factor (FGF) signaling play important roles in coordinating development of the mouse inner, middle, and outer ears. Extracellular signal-regulated kinases (ERKs) are among the effectors...