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Lindsay E Yandek

Explore the profile of Lindsay E Yandek including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 8
Citations 230
Followers 0
Related Specialties
Biochemistry
Biophysics
Microbiology
Top 10 Co-Authors
Paulo F F Almeida
Antje Pokorny
Michael E Harris
Hsuan-Chun Lin
Frank E Campbell
Anders Floren
Lei Sun
Ino Gjermeni
Vernon E Anderson
Courtney N Niland
Published In
Biophys J
Biochemistry
J Biol Chem
Nature
J Mol Biol
Affiliations
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Recent Articles
1.
Determination of relative rate constants for in vitro RNA processing reactions by internal competition
Lin H, Yandek L, Gjermeni I, Harris M
Anal Biochem . 2014 Sep; 467:54-61. PMID: 25173512
Studies of RNA recognition and catalysis typically involve measurement of rate constants for reactions of individual RNA sequence variants by fitting changes in substrate or product concentration to exponential or...
2.
Hidden specificity in an apparently nonspecific RNA-binding protein
Guenther U, Yandek L, Niland C, Campbell F, Anderson D, Anderson V, et al.
Nature . 2013 Sep; 502(7471):385-8. PMID: 24056935
Nucleic-acid-binding proteins are generally viewed as either specific or nonspecific, depending on characteristics of their binding sites in DNA or RNA. Most studies have focused on specific proteins, which identify...
3.
Alternative substrate kinetics of Escherichia coli ribonuclease P: determination of relative rate constants by internal competition
Yandek L, Lin H, Harris M
J Biol Chem . 2013 Jan; 288(12):8342-8354. PMID: 23362254
A single enzyme, ribonuclease P (RNase P), processes the 5' ends of tRNA precursors (ptRNA) in cells and organelles that carry out tRNA biosynthesis. This substrate population includes over 80...
4.
Binding of C5 protein to P RNA enhances the rate constant for catalysis for P RNA processing of pre-tRNAs lacking a consensus (+ 1)/C(+ 72) pair
Sun L, Campbell F, Yandek L, Harris M
J Mol Biol . 2009 Nov; 395(5):1019-37. PMID: 19917291
The RNA subunit of the ribonucleoprotein enzyme ribonuclease P (RNase P (P RNA) contains the active site, but binding of Escherichia coli RNase P protein (C5) to P RNA increases...
5.
Wasp mastoparans follow the same mechanism as the cell-penetrating peptide transportan 10
Yandek L, Pokorny A, Almeida P
Biochemistry . 2009 Jul; 48(30):7342-51. PMID: 19594111
We have been examining the mechanism and kinetics of the interactions of a selected set of peptides with phospholipid membranes in a quantitative manner. This set was chosen to cover...
6.
Small changes in the primary structure of transportan 10 alter the thermodynamics and kinetics of its interaction with phospholipid vesicles
Yandek L, Pokorny A, Almeida P
Biochemistry . 2008 Feb; 47(9):3051-60. PMID: 18260641
The kinetics and thermodynamics of binding of transportan 10 (tp10) and four of its variants to phospholipid vesicles, and the kinetics of peptide-induced dye efflux, were compared. Tp10 is a...
7.
Mechanism of the cell-penetrating peptide transportan 10 permeation of lipid bilayers
Yandek L, Pokorny A, Floren A, Knoelke K, Langel U, Almeida P
Biophys J . 2007 Jan; 92(7):2434-44. PMID: 17218466
The mechanism of the interaction between the cell-penetrating peptide transportan 10 (tp10) and phospholipid membranes was investigated. Tp10 induces graded release of the contents of phospholipid vesicles. The kinetics of...
8.
Temperature and composition dependence of the interaction of delta-lysin with ternary mixtures of sphingomyelin/cholesterol/POPC
Pokorny A, Yandek L, Elegbede A, Hinderliter A, Almeida P
Biophys J . 2006 Jun; 91(6):2184-97. PMID: 16798807
The kinetics of carboxyfluorescein efflux induced by the amphipathic peptide delta-lysin from vesicles of porcine brain sphingomyelin (BSM), 1-palmitoyl-2-oleoyl-phosphatidylcholine (POPC), and cholesterol (Chol) were investigated as a function of temperature...