Antje Pokorny
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Explore the profile of Antje Pokorny including associated specialties, affiliations and a list of published articles.
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30
Citations
839
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Recent Articles
1.
Raskovic D, Alvarado G, Hines K, Xu L, Gatto C, Wilkinson B, et al.
Biochim Biophys Acta Biomembr
. 2024 Nov;
1867(1):184395.
PMID: 39500386
Staphylococcus aureus readily adapts to various environments and quickly develops antibiotic resistance, which has led to an increase in multidrug-resistant infections. Hence, S. aureus presents a significant global health issue...
2.
Barbarek S, Shah R, Paul S, Alvarado G, Appala K, Phillips C, et al.
J Bacteriol
. 2024 Jul;
206(7):e0018724.
PMID: 38953643
Importance: We show that can use its known ability to incorporate exogenous fatty acids to enhance its growth at low temperatures. Individual species of phosphatidylglycerols and diglycosyldiacylglycerols bearing one or...
3.
Raskovic D, Alvarado G, Hines K, Xu L, Gatto C, Wilkinson B, et al.
bioRxiv
. 2024 May;
PMID: 38746422
readily adapts to various environments and quickly develops antibiotic resistance, which has led to an increase in multidrug-resistant infections. Hence, presents a significant global health issue and its adaptations to...
4.
Barbarek S, Shah R, Paul S, Alvarado G, Appala K, Henderson E, et al.
bioRxiv
. 2024 Feb;
PMID: 38352554
It is well established that can incorporate exogenous straight-chain unsaturated fatty acids (SCUFAs) into membrane phospho- and glyco-lipids from various sources in supplemented culture media, and when growing in an...
5.
Wu T, Kumar M, Zhang J, Zhao S, Drobizhev M, McCollum M, et al.
Sci Adv
. 2023 Mar;
9(9):eadd2058.
PMID: 36857451
Synaptic zinc ion (Zn) has emerged as a key neuromodulator in the brain. However, the lack of research tools for directly tracking synaptic Zn in the brain of awake animals...
6.
Pokorny A, Almeida P
J Membr Biol
. 2021 Feb;
254(1):97-108.
PMID: 33620544
The mechanism of the antimicrobial peptide daptomycin is reviewed and discussed. Daptomycin is a last-resort antibiotic in current use against drug-resistant bacterial infections. Many models have been proposed for its...
7.
Hines K, Alvarado G, Chen X, Gatto C, Pokorny A, Alonzo 3rd F, et al.
mSphere
. 2020 Jun;
5(3).
PMID: 32554713
can incorporate exogenous straight-chain unsaturated and saturated fatty acids (SCUFAs and SCFAs, respectively) to replace some of the normally biosynthesized branched-chain fatty acids and SCFAs. In this study, the impact...
8.
Pokorny A, Khatib T, Stevenson H
J Phys Chem B
. 2018 Sep;
122(39):9137-9146.
PMID: 30247034
Daptomycin is a cyclic lipopeptide of clinical importance in the treatment of multidrug resistant infections, including those caused by methicillin-resistant S. aureus strains. Similar to many other antimicrobial peptides, daptomycin...
9.
Kreutzberger M, Pokorny A, Almeida P
Langmuir
. 2017 Nov;
33(47):13669-13679.
PMID: 29130685
Daptomycin is an acidic, 13-amino acid, cyclic polypeptide that contains a number of nonproteinogenic residues and is modified at its N-terminus with a decanoyl chain. It has been in clinical...
10.
Khatib T, Stevenson H, Yeaman M, Bayer A, Pokorny A
Antimicrob Agents Chemother
. 2016 May;
60(8):5051-3.
PMID: 27216066
The cytoplasmic membrane of Staphylococcus aureus contains ∼20 mol% of the net cationic lipid lysyl-phosphatidylglycerol (LPG). Elevated fractions of LPG are associated with increased resistance to cationic antibiotics, including the...