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Frank E Campbell

Explore the profile of Frank E Campbell including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 160
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Recent Articles
1.
Guenther U, Yandek L, Niland C, Campbell F, Anderson D, Anderson V, et al.
Nature . 2013 Sep; 502(7471):385-8. PMID: 24056935
Nucleic-acid-binding proteins are generally viewed as either specific or nonspecific, depending on characteristics of their binding sites in DNA or RNA. Most studies have focused on specific proteins, which identify...
2.
Koutmou K, Zahler N, Kurz J, Campbell F, Harris M, Fierke C
J Mol Biol . 2009 Nov; 396(1):195-208. PMID: 19932118
Bacterial ribonuclease P (RNase P) catalyzes the cleavage of 5' leader sequences from precursor tRNAs (pre-tRNAs). Previously, all known substrate nucleotide specificities in this system are derived from RNA-RNA interactions...
3.
Sun L, Campbell F, Yandek L, Harris M
J Mol Biol . 2009 Nov; 395(5):1019-37. PMID: 19917291
The RNA subunit of the ribonucleoprotein enzyme ribonuclease P (RNase P (P RNA) contains the active site, but binding of Escherichia coli RNase P protein (C5) to P RNA increases...
4.
Sun L, Campbell F, Zahler N, Harris M
EMBO J . 2006 Aug; 25(17):3998-4007. PMID: 16932744
The ribonucleoprotein enzyme RNase P processes all pre-tRNAs, yet some substrates apparently lack consensus elements for recognition. Here, we compare binding affinities and cleavage rates of Escherichia coli pre-tRNAs that...
5.
Guo X, Campbell F, Sun L, Christian E, Anderson V, Harris M
J Mol Biol . 2006 Jun; 360(1):190-203. PMID: 16750220
The pre-tRNA processing enzyme ribonuclease P is a ribonucleoprotein. In Escherichia coli assembly of the holoenzyme involves binding of the small (119 amino acid residue) C5 protein to the much...