Lee H Wong
Overview
Explore the profile of Lee H Wong including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
46
Citations
2446
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Winstanley Y, Rose R, Sobinoff A, Wu L, Adhikari D, Zhang Q, et al.
Nat Commun
. 2025 Mar;
16(1):2527.
PMID: 40087268
The initial setting of telomere length during early life in each individual has a major influence on lifetime risk of aging-associated diseases; however there is limited knowledge of biological signals...
2.
Wong L, Tremethick D
Nat Rev Genet
. 2024 Aug;
26(2):82-104.
PMID: 39138293
Histones are integral components of eukaryotic chromatin that have a pivotal role in the organization and function of the genome. The dynamic regulation of chromatin involves the incorporation of histone...
3.
Wong L, Brettingham-Moore K, Chan L, Quach J, Anderson M, Northrop E, et al.
Genome Res
. 2024 Jul;
34(6):979-980.
PMID: 39043439
No abstract available.
4.
Chakma C, Garvie A, Wong L, Good-Jacobson K
Methods Mol Biol
. 2024 Jul;
2826:47-54.
PMID: 39017884
Immunofluorescence microscopy is a powerful technique using fluorescently labelled antibodies which can be used to visualize proteins in the nucleus. A key advantage of this method is that it can...
5.
Leon N, Le T, Garvie A, Wong L, Bagheri-Fam S, Harley V
iScience
. 2024 Apr;
27(5):109629.
PMID: 38616920
ATR-X (alpha thalassemia, mental retardation, X-linked) syndrome features genital and testicular abnormalities including atypical genitalia and small testes with few seminiferous tubules. Our mouse model recapitulated the testicular defects when...
6.
Voon H, Hii L, Garvie A, Udugama M, Krug B, Russo C, et al.
Genome Biol
. 2023 Dec;
24(1):284.
PMID: 38066546
Background: Point mutations in histone variant H3.3 (H3.3K27M, H3.3G34R) and the H3.3-specific ATRX/DAXX chaperone complex are frequent events in pediatric gliomas. These H3.3 point mutations affect many chromatin modifications but...
7.
Voon H, Wong L
Front Oncol
. 2023 Jan;
12:1104129.
PMID: 36686810
Pediatric high grade gliomas (HGG) are lethal tumors which are currently untreatable. A number of recent studies have provided much needed insights into the mutations and mechanisms which drive oncogenesis...
8.
Udugama M, Vinod B, Chan F, Hii L, Garvie A, Collas P, et al.
Nucleic Acids Res
. 2022 Apr;
50(8):4500-4514.
PMID: 35451487
Histone H3.3 is an H3 variant which differs from the canonical H3.1/2 at four residues, including a serine residue at position 31 which is evolutionarily conserved. The H3.3 S31 residue...
9.
Canver M, Tripathi P, Bullen M, Olshansky M, Kumar Y, Wong L, et al.
J Biol Chem
. 2020 Sep;
295(47):15797-15809.
PMID: 32994224
Regulatory elements (REs) consist of enhancers and promoters that occupy a significant portion of the noncoding genome and control gene expression programs either in or in Putative REs have been...
10.
Voon H, Udugama M, Lin W, Hii L, Law R, Steer D, et al.
Nat Commun
. 2018 Aug;
9(1):3142.
PMID: 30087349
An array of oncogenic histone point mutations have been identified across a number of different cancer studies. It has been suggested that some of these mutant histones can exert their...