K H Andy Choo
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Explore the profile of K H Andy Choo including associated specialties, affiliations and a list of published articles.
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53
Citations
2362
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Recent Articles
1.
Wong L, Brettingham-Moore K, Chan L, Quach J, Anderson M, Northrop E, et al.
Genome Res
. 2024 Jul;
34(6):979-980.
PMID: 39043439
No abstract available.
2.
Garsed D, Marshall O, Corbin V, Hsu A, Stefano L, Schroder J, et al.
Cancer Cell
. 2014 Dec;
26(5):653-67.
PMID: 25517748
We isolated and analyzed, at single-nucleotide resolution, cancer-associated neochromosomes from well- and/or dedifferentiated liposarcomas. Neochromosomes, which can exceed 600 Mb in size, initially arise as circular structures following chromothripsis involving...
3.
Chang F, McGhie J, Chan F, Tang M, Anderson M, Mann J, et al.
Nucleic Acids Res
. 2013 Feb;
41(8):4447-58.
PMID: 23444137
We have previously shown that α-thalassemia mental retardation X-linked (ATRX) and histone H3.3 are key regulators of telomeric chromatin in mouse embryonic stem cells. The function of ATRX and H3.3...
4.
Ip J, Canham P, Choo K, Inaba Y, Jacobs S, Kalitsis P, et al.
PLoS Genet
. 2012 Sep;
8(9):e1002919.
PMID: 22969435
Reduced DNA methylation has been reported in DICER1-deficient mouse ES cells. Reductions seen at pericentric satellite repeats have suggested that siRNAs are required for the proper assembly of heterochromatin. More...
5.
Ren H, Collins V, Clarke S, Han J, Lam P, Clay F, et al.
Evid Based Complement Alternat Med
. 2012 Jun;
2012:841810.
PMID: 22719790
Tai chi exercise has been shown to improve physiological and psychosocial functions, well-being, quality of life, and disease conditions. The biological mechanisms by which tai chi exerts its holistic effects...
6.
Kalitsis P, Choo K
Chromosoma
. 2012 Apr;
121(4):327-40.
PMID: 22527114
The centromere is a chromosomal structure that is essential for the accurate segregation of replicated eukaryotic chromosomes to daughter cells. In most centromeres, the underlying DNA is principally made up...
7.
Green L, Kalitsis P, Chang T, Cipetic M, Kim J, Marshall O, et al.
J Cell Sci
. 2012 Feb;
125(Pt 6):1591-604.
PMID: 22344259
In vertebrates, two condensin complexes exist, condensin I and condensin II, which have differing but unresolved roles in organizing mitotic chromosomes. To dissect accurately the role of each complex in...
8.
Chan F, Marshall O, Saffery R, Kim B, Earle E, Choo K, et al.
Proc Natl Acad Sci U S A
. 2012 Feb;
109(6):1979-84.
PMID: 22308327
Transcription of the centromeric regions has been reported to occur in G1 and S phase in different species. Here, we investigate whether transcription also occurs and plays a functional role...
9.
Marshall O, Choo K
Chromosoma
. 2011 Nov;
121(2):169-79.
PMID: 22080934
Although centromere protein B (CENP-B) is a highly conserved mammalian centromere protein, its function remains unknown. The presence of the protein is required to form artificial satellite DNA-based centromeres de...
10.
Ren H, Collins V, Fernandez F, Quinlan S, Griffiths L, Choo K
Headache
. 2010 Jul;
50(6):965-72.
PMID: 20618815
Objective: To evaluate relative telomere length of female migraine patients. Background: Migraine is a debilitating disorder affecting 6-28% of the population. Studies on the mechanisms of migraine have demonstrated genetic...