Lee Ann Feeney
Overview
Explore the profile of Lee Ann Feeney including associated specialties, affiliations and a list of published articles.
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6
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160
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Recent Articles
1.
Maianti J, Kanazawa H, Dozzo P, Matias R, Feeney L, Armstrong E, et al.
ACS Chem Biol
. 2014 Jul;
9(9):2067-73.
PMID: 25019242
Aminoglycoside antibiotics are pseudosaccharides decorated with ammonium groups that are critical for their potent broad-spectrum antibacterial activity. Despite over three decades of speculation whether or not modulation of pKa is...
2.
Hanessian S, Giguere A, Grzyb J, Maianti J, Saavedra O, Aggen J, et al.
ACS Med Chem Lett
. 2014 Jun;
2(12):924-8.
PMID: 24900282
Deoxygenation of the diol groups in rings A and D of neomycin in combination with the introduction of an N1-(l)-HABA group in the 2-deoxystreptamine subunit (ring B) leads to a...
3.
Hanessian S, Maianti J, Matias R, Feeney L, Armstrong E
Org Lett
. 2011 Nov;
13(24):6476-9.
PMID: 22085292
Biosynthetically inspired manipulation of the antibiotic paromomycin led, in six high-yielding steps, to a ring A harboring an α,β-unsaturated 6'-aldehyde and an allylic 3'-methylcarbonate group. Tsuji deoxygenation in the presence...
4.
Aggen J, Armstrong E, Goldblum A, Dozzo P, Linsell M, Gliedt M, et al.
Antimicrob Agents Chemother
. 2010 Sep;
54(11):4636-42.
PMID: 20805391
ACHN-490 is a neoglycoside, or "next-generation" aminoglycoside (AG), that has been identified as a potentially useful agent to combat drug-resistant bacteria emerging in hospitals and health care facilities around the...
5.
Zapor M, Barber M, Summers A, Miller G, Feeney L, Eberly L, et al.
Antimicrob Agents Chemother
. 2010 Apr;
54(7):3015-7.
PMID: 20404121
We determined the in vitro MIC of arbekacin against 200 Acinetobacter isolates recovered from wounded soldiers. The median MIC was 2 microg/ml (range, 0.5 to > 64 microg/ml). A total...
6.
Indukuri H, Castro S, Liao S, Feeney L, Dorsch M, Coyle A, et al.
Virology
. 2006 Jun;
353(1):155-65.
PMID: 16806387
Respiratory syncytial virus (RSV)-induced chemokine gene expression occurs through the activation of a subset of transcription factors, including Interferon Regulatory Factor (IRF)-3. In this study, we have investigated the signaling...