Leanne Wallace
Overview
Explore the profile of Leanne Wallace including associated specialties, affiliations and a list of published articles.
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Articles
35
Citations
1211
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Recent Articles
1.
Yap C, Henders A, Alvares G, Wood D, Krause L, Tyson G, et al.
Cell
. 2024 Jan;
187(2):495-510.
PMID: 38242089
No abstract available.
2.
Yap C, Henders A, Alvares G, Giles C, Huynh K, Nguyen A, et al.
Nat Med
. 2023 Apr;
29(4):936-949.
PMID: 37076741
Autism omics research has historically been reductionist and diagnosis centric, with little attention paid to common co-occurring conditions (for example, sleep and feeding disorders) and the complex interplay between molecular...
3.
Freydenzon A, Nabais M, Lin T, Williams K, Wallace L, Henders A, et al.
Sci Rep
. 2022 Jun;
12(1):10582.
PMID: 35732753
Individuals encounter varying environmental exposures throughout their lifetimes. Some exposures such as smoking are readily observed and have high personal recall; others are more indirect or sporadic and might only...
4.
Hop P, Zwamborn R, Hannon E, Shireby G, Nabais M, Walker E, et al.
Sci Transl Med
. 2022 Feb;
14(633):eabj0264.
PMID: 35196023
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with an estimated heritability between 40 and 50%. DNA methylation patterns can serve as proxies of (past) exposures and disease progression,...
5.
van Rheenen W, van der Spek R, Bakker M, van Vugt J, Hop P, Zwamborn R, et al.
Nat Genet
. 2022 Feb;
54(3):361.
PMID: 35102318
No abstract available.
6.
Restuadi R, Steyn F, Kabashi E, Ngo S, Cheng F, Nabais M, et al.
Genome Med
. 2022 Jan;
14(1):7.
PMID: 35042540
Background: Amyotrophic lateral sclerosis (ALS) is a complex, late-onset, neurodegenerative disease with a genetic contribution to disease liability. Genome-wide association studies (GWAS) have identified ten risk loci to date, including...
7.
van Rheenen W, van der Spek R, Bakker M, van Vugt J, Hop P, Zwamborn R, et al.
Nat Genet
. 2021 Dec;
53(12):1636-1648.
PMID: 34873335
Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease with a lifetime risk of one in 350 people and an unmet need for disease-modifying therapies. We conducted a cross-ancestry genome-wide...
8.
Yap C, Henders A, Alvares G, Wood D, Krause L, Tyson G, et al.
Cell
. 2021 Nov;
184(24):5916-5931.e17.
PMID: 34767757
There is increasing interest in the potential contribution of the gut microbiome to autism spectrum disorder (ASD). However, previous studies have been underpowered and have not been designed to address...
9.
Restuadi R, Garton F, Benyamin B, Lin T, Williams K, Vinkhuyzen A, et al.
Eur J Hum Genet
. 2021 Apr;
30(5):532-539.
PMID: 33907316
Amyotrophic Lateral Sclerosis (ALS) is recognised to be a complex neurodegenerative disease involving both genetic and non-genetic risk factors. The underlying causes and risk factors for the majority of cases...
10.
Nabais M, Laws S, Lin T, Vallerga C, Armstrong N, Blair I, et al.
Genome Biol
. 2021 Mar;
22(1):90.
PMID: 33771206
Background: People with neurodegenerative disorders show diverse clinical syndromes, genetic heterogeneity, and distinct brain pathological changes, but studies report overlap between these features. DNA methylation (DNAm) provides a way to...