Laura E Herring
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Explore the profile of Laura E Herring including associated specialties, affiliations and a list of published articles.
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102
Citations
1659
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Recent Articles
1.
Parsons V, Vadlamudi S, Voos K, Rohy A, Moxley A, Cannon M, et al.
Diabetologia
. 2025 Mar;
PMID: 40064677
Aims/hypothesis: Components of the insulin processing and secretion pathways remain incompletely understood. Here, we examined a genome-wide association study (GWAS) signal for plasma proinsulin levels. Lead GWAS variant rs150781447-T encodes...
2.
Busch R, Doty C, Mills C, Latifi F, Herring L, Konjufca V, et al.
bioRxiv
. 2025 Mar;
PMID: 40060473
Septins are a family of GTP-binding proteins found in many eukaryotic lineages. Although highly conserved throughout many eukaryotes, their functions vary across species. In , the etiological agent of invasive...
3.
Ghoshal A, Tse E, Hossain M, Asressu K, Merten E, Sears J, et al.
Sci Rep
. 2025 Mar;
15(1):7264.
PMID: 40025188
Chikungunya is a mosquito-borne viral disease that causes fever and severe joint pain for which there is no direct acting drug treatments. Vinyl sulfone SGC-NSP2PRO-1 (3) was identified as a...
4.
Uguen M, Shell D, Silva M, Deng Y, Li F, Szewczyk M, et al.
Nat Commun
. 2025 Feb;
16(1):1905.
PMID: 39994194
A promising drug target, SETDB1, is a dual methyl-lysine (Kme) reader and methyltransferase implicated in cancer and neurodegenerative disease progression. To help understand the role of the triple Tudor domain...
5.
Hickman E, Carberry V, Carberry C, Cooper B, Mordant A, Mills A, et al.
PLoS One
. 2025 Jan;
20(1):e0315743.
PMID: 39854355
Growing evidence supports the importance of extracellular vesicle (EV) as mediators of communication in pathological processes, including those underlying respiratory disease. However, establishing methods for isolating and characterizing EVs remains...
6.
Shirley D, Nandakumar M, Cabrera A, Yiu B, Puumala E, Liu Z, et al.
bioRxiv
. 2025 Jan;
PMID: 39829896
is a growing health concern as the leading causal agent of systemic candidiasis, a life-threatening fungal infection with a mortality rate of ~40% despite best available therapy. Yck2, a fungal...
7.
Chiou L, Jayaprakash D, Droby G, Zhang X, Yang Y, Mills C, et al.
bioRxiv
. 2025 Jan;
PMID: 39829812
The DNA damage response (DDR) mechanisms that allow cells to tolerate DNA replication stress are critically important for genome stability and cell viability. Using an unbiased genetic screen we identify...
8.
Song F, Tsahouridis O, Stucchi S, Walhart T, Mendell S, Hardy P, et al.
Nat Immunol
. 2025 Jan;
26(2):279-293.
PMID: 39779871
Chimeric antigen receptor T cells (CAR T cells) with T stem (T) cell-like phenotypic characteristics promote sustained antitumor effects. We performed an unbiased and automated high-throughput screen of a kinase-focused...
9.
Ghoshal A, Tse E, Hossain M, Asressu K, Merten E, Sears J, et al.
Res Sq
. 2024 Nov;
PMID: 39606462
RA-0003022 () was identified as a high-quality covalent chemical probe for nsP2 cysteine protease (nsP2pro). Isoxazole covalently captured the active site C478 and inactivated the enzyme with a / ratio...
10.
Vitucci E, Carberry C, Payton A, Herring L, Mordant A, Kim Y, et al.
Environ Res
. 2024 Nov;
264(Pt 2):120395.
PMID: 39571711
Wildfires adversely impact air quality and public health worldwide. Exposures to wildfire smoke are linked to adverse health outcomes, including cardiopulmonary diseases. Critical research gaps remain surrounding the underlying biological...