Lars E T Jansen
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Explore the profile of Lars E T Jansen including associated specialties, affiliations and a list of published articles.
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Articles
39
Citations
2745
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Recent Articles
21.
Stankovic A, Jansen L
J Cell Biol
. 2013 Jan;
200(1):7-8.
PMID: 23277428
The kinetochore forms the site of attachment for mitotic spindle microtubules driving chromosome segregation. The interdependent protein interactions in this large structure have made it difficult to dissect the function...
22.
Gomez-Rodriguez M, Jansen L
Curr Opin Genet Dev
. 2012 Dec;
23(2):219-27.
PMID: 23219400
Chromatin-based epigenetic inheritance cooperates with cis-acting DNA sequence information to propagate gene expression states and chromosome architecture across cell division cycles. Histone proteins and their modifications are central components of...
23.
Bodor D, Rodriguez M, Moreno N, Jansen L
Curr Protoc Cell Biol
. 2012 Nov;
Chapter 8:Unit8.8.
PMID: 23129118
Assessment of protein dynamics in living cells is crucial for understanding their biological properties and functions. The SNAP-tag, a self labeling suicide enzyme, presents a tool with unique features that...
24.
Valente L, Silva M, Jansen L
Chromosome Res
. 2012 Jun;
20(5):481-92.
PMID: 22740047
All living organisms require accurate mechanisms to faithfully inherit their genetic material during cell division. The centromere is a unique locus on each chromosome that supports a multiprotein structure called...
25.
Mata J, Lopes T, Gardner R, Jansen L
PLoS One
. 2012 Mar;
7(2):e32646.
PMID: 22393430
Gene targeting protocols for mammalian cells remain inefficient and labor intensive. Here we describe FASTarget, a rapid, fluorescent cell sorting based strategy to isolate rare gene targeting events in human...
26.
27.
Ray-Gallet D, Woolfe A, Vassias I, Pellentz C, Lacoste N, Puri A, et al.
Mol Cell
. 2011 Dec;
44(6):928-41.
PMID: 22195966
Establishment of a proper chromatin landscape is central to genome function. Here, we explain H3 variant distribution by specific targeting and dynamics of deposition involving the CAF-1 and HIRA histone...
28.
Silva M, Bodor D, Stellfox M, Martins N, Hochegger H, Foltz D, et al.
Dev Cell
. 2011 Dec;
22(1):52-63.
PMID: 22169070
Centromeres form the site of chromosome attachment to microtubules during mitosis. Identity of these loci is maintained epigenetically by nucleosomes containing the histone H3 variant CENP-A. Propagation of CENP-A chromatin...
29.
Bergmann J, Rodriguez M, Martins N, Kimura H, Kelly D, Masumoto H, et al.
EMBO J
. 2010 Dec;
30(2):328-40.
PMID: 21157429
Kinetochores assemble on distinct 'centrochromatin' containing the histone H3 variant CENP-A and interspersed nucleosomes dimethylated on H3K4 (H3K4me2). Little is known about how the chromatin environment at active centromeres governs...
30.
Samoshkin A, Arnaoutov A, Jansen L, Ouspenski I, Dye L, Karpova T, et al.
PLoS One
. 2009 Aug;
4(8):e6831.
PMID: 19714251
Condensins I and II in vertebrates are essential ATP-dependent complexes necessary for chromosome condensation in mitosis. Condensins depletion is known to perturb structure and function of centromeres, however the mechanism...