Krista McCutcheon
Overview
Explore the profile of Krista McCutcheon including associated specialties, affiliations and a list of published articles.
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9
Citations
330
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0
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Recent Articles
1.
Feng J, Xu Y, Barauskas O, Perry J, Ahmadyar S, Stepan G, et al.
Antimicrob Agents Chemother
. 2015 Nov;
60(2):806-17.
PMID: 26596942
Toxicity has emerged during the clinical development of many but not all nucleotide inhibitors (NI) of hepatitis C virus (HCV). To better understand the mechanism for adverse events, clinically relevant...
2.
Wang X, Quarmby V, Ng C, Chuntharapai A, Shek T, Eigenbrot C, et al.
MAbs
. 2013 Jun;
5(4):540-54.
PMID: 23774668
Pharmacokinetic (PK) and immunohistochemistry (IHC) assays are essential to the evaluation of the safety and efficacy of therapeutic monoclonal antibodies (mAb) during drug development. These methods require reagents with a...
3.
Pantua H, Diao J, Ultsch M, Hazen M, Mathieu M, McCutcheon K, et al.
J Mol Biol
. 2013 Mar;
425(11):1899-1914.
PMID: 23458406
Hepatitis C virus (HCV) infection is a major cause of liver disease and hepatocellular carcinoma. Glycan shielding has been proposed to be a mechanism by which HCV masks broadly neutralizing...
4.
Castellana N, McCutcheon K, Pham V, Harden K, Nguyen A, Young J, et al.
Proteomics
. 2011 Jan;
11(3):395-405.
PMID: 21268269
A mouse hybridoma antibody directed against a member of the tumour necrosis factor (TNF)-superfamily, lymphotoxin-alpha (LT-α), was isolated from stored mouse ascites and purified to homogeneity. After more than a...
5.
Asundi J, Reed C, Arca J, McCutcheon K, Ferrando R, Clark S, et al.
Clin Cancer Res
. 2011 Jan;
17(5):965-75.
PMID: 21245091
Purpose: To identify and evaluate targets amenable to antibody therapy in melanoma. Experimental Design: We searched for mRNA transcripts coding for cell-surface proteins with expression patterns similar to that of...
6.
Bais C, Wu X, Yao J, Yang S, Crawford Y, McCutcheon K, et al.
Cell
. 2010 Apr;
141(1):166-77.
PMID: 20371352
It has been recently reported that treatment with an anti-placenta growth factor (PlGF) antibody inhibits metastasis and primary tumor growth. Here we show that, although anti-PlGF treatment inhibited wound healing,...
7.
McCutcheon K
Methods Mol Biol
. 2008 Feb;
418:187-208.
PMID: 18287660
Analytical methods characterizing the immunogenicity of antigens are useful for monitoring, characterizing and predicting antibody responses to therapeutic biologics or vaccines. Distinct Luminex microspheres coupled with protein G, anti-human immunoglobulin...
8.
McCutcheon K, OHara E, Fei D
Immunol Invest
. 2005 Jun;
34(2):199-213.
PMID: 15921159
Analytical methods characterizing the immunogenicity of therapeutic proteins are useful for monitoring, characterizing and predicting reactions to biopharmaceuticals. A multiplexed assay capable of isotyping the specific IgG, IgA, IgM and...
9.
Singaraja R, Hadano S, Metzler M, Givan S, Wellington C, Warby S, et al.
Hum Mol Genet
. 2002 Oct;
11(23):2815-28.
PMID: 12393793
Huntington disease (HD) is caused by polyglutamine [poly(Q)] expansion in the protein huntingtin (htt). Although the exact mechanism of disease progression remains to be elucidated, altered interactions of mutant htt...