Kirsi H Pietilainen
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Explore the profile of Kirsi H Pietilainen including associated specialties, affiliations and a list of published articles.
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206
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9543
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Recent Articles
21.
Lee S, Garske K, Arasu U, Kar A, Miao Z, Alvarez M, et al.
EBioMedicine
. 2024 Jul;
106:105232.
PMID: 38991381
Background: Abdominal obesity increases the risk for non-alcoholic fatty liver disease (NAFLD), now known as metabolic dysfunction-associated steatotic liver disease (MASLD). Methods: To elucidate the directional cell-type level biological mechanisms...
22.
Ahola A, Suojanen L, Joki A, Pietilainen K
Prev Med
. 2024 Jun;
185():108032.
PMID: 38851400
Objective: To investigate cross-sectional associations between loneliness and health, health behaviours, and perceptions in Finnish individuals with overweight or obesity (BMI ≥25 kg/m). Methods: We used baseline data from patients...
23.
Christiansen C, Potier L, Martin T, Villicana S, Castillo-Fernandez J, Mangino M, et al.
EBioMedicine
. 2024 Apr;
103:105096.
PMID: 38574408
Background: Type 2 diabetes (T2D) susceptibility is influenced by genetic and environmental factors. Previous findings suggest DNA methylation as a potential mechanism in T2D pathogenesis and progression. Methods: We profiled...
24.
Kar A, Alvarez M, Garske K, Huang H, Lee S, Deal M, et al.
Genome Med
. 2024 Jan;
16(1):19.
PMID: 38297378
Background: Age and obesity are dominant risk factors for several common cardiometabolic disorders, and both are known to impair adipose tissue function. However, the underlying cellular and genetic factors linking...
25.
Fohr T, Hendrix A, Kankaanpaa A, Laakkonen E, Kujala U, Pietilainen K, et al.
Int J Obes (Lond)
. 2024 Jan;
48(6):778-787.
PMID: 38273034
Background: Metabolic syndrome (MetS) is associated with premature aging, but whether this association is driven by genetic or lifestyle factors remains unclear. Methods: Two independent discovery cohorts, consisting of twins...
26.
Kupila S, Berntzen B, Muniandy M, Ahola A, Kaprio J, Rissanen A, et al.
PLoS One
. 2023 Dec;
18(12):e0294162.
PMID: 38055659
Objective: The relationship between obesity and mental health is complex and is moderated by the level of obesity, age, sex, and social and genetic factors. In the current study, we...
27.
Biehl A, Venalainen M, Suojanen L, Kupila S, Ahola A, Pietilainen K, et al.
Sci Rep
. 2023 Nov;
13(1):20661.
PMID: 38001145
This study aims to develop and validate a modeling framework to predict long-term weight change on the basis of self-reported weight data. The aim is to enable focusing resources of...
28.
Berntzen B, Palviainen T, Silventoinen K, Pietilainen K, Kaprio J
Obesity (Silver Spring)
. 2023 Nov;
31(12):3086-3094.
PMID: 37987187
Objective: This study investigated 36-year BMI trajectories in twins whose BMI in young adulthood was below, within, or above their genetically predicted BMI, with a focus on twin pairs with...
29.
Heinonen S, Saarinen T, Merilainen S, Sammalkorpi H, Penttila A, Koivikko M, et al.
Obesity (Silver Spring)
. 2023 Nov;
31(12):2909-2923.
PMID: 37987183
Objective: Although it has been suggested that one-anastomosis gastric bypass (OAGB) is metabolically superior to the "gold standard," i.e., Roux-en-Y gastric bypass (RYGB), there is little robust evidence to prove...
30.
Chaurasiya V, Pham D, Harju J, Juuti A, Penttila A, Emmagouni S, et al.
Exp Cell Res
. 2023 Oct;
433(2):113819.
PMID: 37852349
Communication between adipocytes and endothelial cells (EC) is suggested to play an important role in the metabolic function of white adipose tissue. In order to generate tools to investigate in...