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Kirsi H Pietilainen

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Articles 206
Citations 9543
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Ojala R, Hentila J, Lietzen M, Arponen M, Heiskanen M, Honkala S, et al.
Diabetes Obes Metab . 2023 Oct; 26(1):251-261. PMID: 37818602
Aim: High body weight is a protective factor against osteoporosis, but obesity also suppresses bone metabolism and whole-body insulin sensitivity. However, the impact of body weight and regular training on...
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Kaseva N, Kuula J, Sandboge S, Hauta-Alus H, Bjorkqvist J, Hovi P, et al.
Pediatr Res . 2023 Sep; 95(1):316-324. PMID: 37758863
Background: Preterm survivors have increased risk for impaired cardiometabolic health. We assessed glucose regulation and cardiometabolic biomarkers in adult very low birth weight (VLBW, <1500 g) survivors, using siblings as...
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Shrine N, Izquierdo A, Chen J, Packer R, Hall R, Guyatt A, et al.
Nat Genet . 2023 Sep; 55(10):1778-1779. PMID: 37749248
No abstract available.
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Halsey L, Careau V, Ainslie P, Aleman-Mateo H, Andersen L, Anderson L, et al.
Biol Lett . 2023 Sep; 19(9):20230152. PMID: 37727077
There is considerably greater variation in metabolic rates between men than between women, in terms of basal, activity and total (daily) energy expenditure (EE). One possible explanation is that EE...
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U-Din M, de Mello V, Tuomainen M, Raiko J, Niemi T, Fromme T, et al.
Cell Rep . 2023 Sep; 42(9):113131. PMID: 37708023
Cold-induced brown adipose tissue (BAT) activation is considered to improve metabolic health. In murine BAT, cold increases the fundamental molecule for mitochondrial function, nicotinamide adenine dinucleotide (NAD), but limited knowledge...
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Brotman S, Oravilahti A, Rosen J, Alvarez M, Heinonen S, van der Kolk B, et al.
Diabetes . 2023 Aug; 72(11):1707-1718. PMID: 37647564
Article Highlights:
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Garske K, Kar A, Comenho C, Balliu B, Pan D, Bhagat Y, et al.
Nat Commun . 2023 Jul; 14(1):4214. PMID: 37452040
Obesity-induced adipose tissue dysfunction can cause low-grade inflammation and downstream obesity comorbidities. Although preadipocytes may contribute to this pro-inflammatory environment, the underlying mechanisms are unclear. We used human primary preadipocytes...
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Zhu R, Huttunen-Lenz M, Stratton G, Handjieva-Darlenska T, Handjiev S, Sundvall J, et al.
Int J Obes (Lond) . 2023 Jul; 47(9):833-840. PMID: 37420008
Background/objectives: Some individuals with overweight/obesity may be relatively metabolically healthy (MHO) and have a lower risk of cardiovascular disease than those with metabolically unhealthy overweight/obesity (MUO). We aimed to compare...
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Das S, Kar A, Rajkumar S, Lee S, Alvarez M, Pietilainen K, et al.
Arterioscler Thromb Vasc Biol . 2023 Jul; 43(10):1788-1804. PMID: 37409528
Background: Adipocytes are crucial regulators of cardiovascular health. However, not much is known about gene expression profiles of adipocytes residing in nonfat cardiovascular tissues, their genetic regulation, and contribution to...