Kin H Lau
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Explore the profile of Kin H Lau including associated specialties, affiliations and a list of published articles.
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22
Citations
265
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Recent Articles
1.
Blanchett R, Lau K, Pfeifer G
Sci Rep
. 2024 Jun;
14(1):13912.
PMID: 38886487
DNA methylation is an epigenetic mark that plays an important role in defining cancer phenotypes, with global hypomethylation and focal hypermethylation at CpG islands observed in tumors. These methylation marks...
2.
Perez-Mojica J, Enders L, Lau K, Lempradl A
STAR Protoc
. 2023 Sep;
4(3):102535.
PMID: 37682716
Exploring early embryonic gene expression is challenging due to the rate of development and the limited material available. Here, we present a protocol for ordering Drosophila embryos along a developmental...
3.
Liao J, Song S, Gusscott S, Fu Z, VanderKolk I, Busscher B, et al.
Sci Adv
. 2023 Sep;
9(36):eadi2050.
PMID: 37672574
The insulator model explains the workings of the and imprinted domain in the soma, where insulation of the promoter from its enhancers occurs by CTCF in the maternally inherited unmethylated...
4.
Luda K, Longo J, Kitchen-Goosen S, Duimstra L, Ma E, Watson M, et al.
Immunity
. 2023 Jul;
56(9):2021-2035.e8.
PMID: 37516105
Environmental nutrient availability influences T cell metabolism, impacting T cell function and shaping immune outcomes. Here, we identified ketone bodies (KBs)-including β-hydroxybutyrate (βOHB) and acetoacetate (AcAc)-as essential fuels supporting CD8...
5.
Avequin T, Lau K, Waldhart A, Guak H, Dykstra H, Krawczyk C, et al.
iScience
. 2023 Jul;
26(7):107163.
PMID: 37456843
Obese individuals experience low grade inflammation initiated within their adipose tissue. However, the early events that lead to the release of these inflammatory factors from adipose tissue are poorly characterized....
6.
Paul E, Carpenter T, Fitch S, Sheridan R, Lau K, Arora R, et al.
Commun Biol
. 2023 Jul;
6(1):686.
PMID: 37400623
Myometrial stem/progenitor cells (MyoSPCs) have been proposed as the cells of origin for uterine fibroids, but the identity of the MyoSPC has not been well established. We previously identified SUSD2...
7.
Cui W, Huang Z, Jin S, Johnson J, Lau K, Hostetter G, et al.
Cancer Res
. 2023 Jun;
83(15):2480-2495.
PMID: 37272752
Significance: Dysfunction of the Polycomb component RYBP in combination with loss of 5-methylcytosine oxidases promotes widespread hypermethylation of CpG islands in bronchial cells and induces tumorigenesis, resembling changes seen in...
8.
Compton S, Kitchen-Goosen S, DeCamp L, Lau K, Mabvakure B, Vos M, et al.
Mol Cell
. 2023 May;
83(11):1872-1886.e5.
PMID: 37172591
Deregulated inflammation is a critical feature driving the progression of tumors harboring mutations in the liver kinase B1 (LKB1), yet the mechanisms linking LKB1 mutations to deregulated inflammation remain undefined....
9.
Waldhart A, Lau K, Dykstra H, Avequin T, Wu N
iScience
. 2023 May;
26(5):106538.
PMID: 37168572
While TXNIP (thioredoxin interacting protein) in the plasma membrane and vesicular location is known to negatively regulate cellular glucose uptake by facilitating glucose transporter endocytosis, the function of TXNIP in...
10.
Paul E, Carpenter T, Fitch S, Sheridan R, Lau K, Arora R, et al.
bioRxiv
. 2023 Mar;
PMID: 36993447
Myometrial stem/progenitor cells (MyoSPCs) have been proposed as the cells of origin for uterine fibroids, which are benign tumors that develop in the myometrium of most reproductive age women, but...