Tyler J Carpenter
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Explore the profile of Tyler J Carpenter including associated specialties, affiliations and a list of published articles.
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9
Citations
75
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Recent Articles
1.
Paul E, Carpenter T, Pavliscak L, Bennett A, Ochoa-Bernal M, Fazleabas A, et al.
F S Sci
. 2024 Jul;
5(4):369-378.
PMID: 39025326
Objective: To study the possible role for HMGA2 overexpression in differentiated myometrial cells and its potential to induce a stem cell-like or dedifferentiating phenotype and drive fibroid development. Design: Myometrial...
2.
Paul E, Carpenter T, Pavliscak L, Bennett A, Ochoa-Bernal M, Fazleabas A, et al.
bioRxiv
. 2024 May;
PMID: 38712187
Uterine fibroids are prevalent benign tumors in women that exhibit considerable heterogeneity in clinical presentation and molecular characteristics, necessitating a deeper understanding of their etiology and pathogenesis. HMGA2 overexpression has...
3.
Paul E, Carpenter T, Fitch S, Sheridan R, Lau K, Arora R, et al.
Commun Biol
. 2023 Jul;
6(1):686.
PMID: 37400623
Myometrial stem/progenitor cells (MyoSPCs) have been proposed as the cells of origin for uterine fibroids, but the identity of the MyoSPC has not been well established. We previously identified SUSD2...
4.
Paul E, Carpenter T, Fitch S, Sheridan R, Lau K, Arora R, et al.
bioRxiv
. 2023 Mar;
PMID: 36993447
Myometrial stem/progenitor cells (MyoSPCs) have been proposed as the cells of origin for uterine fibroids, which are benign tumors that develop in the myometrium of most reproductive age women, but...
5.
Paul E, Grey J, Carpenter T, Madaj Z, Lau K, Givan S, et al.
JCI Insight
. 2022 Sep;
7(20).
PMID: 36066972
Uterine fibroids (leiomyomas) affect Black women disproportionately compared with women of other races and ethnicities in terms of prevalence, incidence, and severity of symptoms. The causes of this racial disparity...
6.
Paul E, Burns G, Carpenter T, Grey J, Fazleabas A, Teixeira J
Int J Mol Sci
. 2021 Apr;
22(7).
PMID: 33807176
Uterine fibroid tissues are often compared to their matched myometrium in an effort to understand their pathophysiology, but it is not clear whether the myometria of uterine fibroid patients represent...
7.
Ghosh A, Syed S, Kumar M, Carpenter T, Teixeira J, Houairia N, et al.
Cell Rep
. 2020 May;
31(6):107631.
PMID: 32402291
The mesenchymal to epithelial transition (MET) is thought to be involved in the maintenance, repair, and carcinogenesis of the fallopian tube (oviduct) and uterine epithelium. However, conclusive evidence for the...
8.
Patterson A, George J, Chatterjee A, Carpenter T, Wolfrum E, Chesla D, et al.
Hum Reprod
. 2020 Jan;
35(1):44-57.
PMID: 31913469
Study Question: Can endometrial stromal stem/progenitor cell markers, SUSD2 and CD146/CD140b, enrich for human myometrial and fibroid stem/progenitor cells? Summary Answer: SUSD2 enriches for myometrial and fibroid cells that have...
9.
Mukherjee A, Patterson A, George J, Carpenter T, Madaj Z, Hostetter G, et al.
Mol Cancer Ther
. 2018 Jun;
17(9):1995-2003.
PMID: 29898896
Endometrial adenocarcinoma (EndoCA) is the most common gynecologic cancer type in the United States, and its incidence is increasing. The majority of patients are disease-free after surgical resection of stage...