Kevin S Harrod
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Explore the profile of Kevin S Harrod including associated specialties, affiliations and a list of published articles.
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73
Citations
1516
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Recent Articles
1.
Hussain S, Libby E, Lever J, Tipper J, Phillips S, Mazur M, et al.
bioRxiv
. 2024 Jul;
PMID: 38979208
Cigarette smoking is associated with COVID-19 prevalence and severity, but the mechanistic basis for how smoking alters SARS-CoV-2 pathogenesis is unknown. A potential explanation is that smoking alters the expression...
2.
Lever J, Li Q, Pavelkova N, Hussain S, Bakshi S, Ren J, et al.
bioRxiv
. 2024 Jun;
PMID: 38895273
Rationale: The role of MUC5B mucin expression in IPF pathogenesis is unknown. Bleomycin-exposed rodent models do not exhibit sustained fibrosis or airway remodeling. Unlike mice, ferrets have human-like distribution of...
3.
Patton M, Gaggar A, Might M, Erdmann N, Orihuela C, Harrod K
Physiol Rev
. 2023 Aug;
104(1):1-21.
PMID: 37589392
No abstract available.
4.
Earnhardt E, Tipper J, DMello A, Jian M, Conway E, Mobley J, et al.
JCI Insight
. 2023 Jun;
8(14).
PMID: 37318849
Influenza A virus (IAV) infection is commonly complicated by secondary bacterial infections that lead to increased morbidity and mortality. Our recent work demonstrates that IAV disrupts airway homeostasis, leading to...
5.
Margaroli C, Fram T, Sharma N, Patel S, Tipper J, Robison S, et al.
JCI Insight
. 2023 Apr;
8(10).
PMID: 37071484
Neutrophilic inflammation characterizes several respiratory viral infections, including COVID-19-related acute respiratory distress syndrome, although its contribution to disease pathogenesis remains poorly understood. Blood and airway immune cells from 52 patients...
6.
Margaroli C, Fram T, Sharma N, Patel S, Tipper J, Robison S, et al.
Res Sq
. 2023 Mar;
PMID: 36993474
Neutrophilic inflammation characterizes several respiratory viral infections including COVID-19-related ARDS, although its contribution to disease pathogenesis remains poorly understood. Here, we identified two neutrophil subpopulations (A1 and A2) in the...
7.
Fortmann S, Patton M, Frey B, Tipper J, Reddy S, Vieira C, et al.
Blood Adv
. 2023 Mar;
7(15):4200-4214.
PMID: 36920790
Several independent lines of evidence suggest that megakaryocytes are dysfunctional in severe COVID-19. Herein, we characterized peripheral circulating megakaryocytes in a large cohort of inpatients with COVID-19 and correlated the...
8.
Mucociliary clearance augmenting drugs block SARS-CoV-2 replication in human airway epithelial cells
Campos-Gomez J, Fernandez Petty C, Mazur M, Tang L, Solomon G, Joseph R, et al.
Am J Physiol Lung Cell Mol Physiol
. 2023 Feb;
324(4):L493-L506.
PMID: 36809189
The coronavirus disease (COVID-19) pandemic, caused by SARS-CoV-2 coronavirus, is devastatingly impacting human health. A prominent component of COVID-19 is the infection and destruction of the ciliated respiratory cells, which...
9.
DMello A, Lane J, Tipper J, Martinez E, Roussey H, Harrod K, et al.
bioRxiv
. 2023 Feb;
PMID: 36778321
Background: (Spn) is typically an asymptomatic colonizer of the nasopharynx but it also causes pneumonia and disseminated disease affecting various host anatomical sites. Transition from colonization to invasive disease is...
10.
Patton M, Orihuela C, Harrod K, Bhuiyan M, Dominic P, Kevil C, et al.
Crit Care
. 2023 Jan;
27(1):34.
PMID: 36691080
Background: Recent single-center reports have suggested that community-acquired bacteremic co-infection in the context of Coronavirus disease 2019 (COVID-19) may be an important driver of mortality; however, these reports have not...