Kevin R W Ngoei
Overview
Explore the profile of Kevin R W Ngoei including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
554
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Ovens A, Gee Y, Ling N, Yu D, Hardee J, Chung J, et al.
Biochem J
. 2022 May;
479(11):1181-1204.
PMID: 35552369
The AMP-activated protein kinase (AMPK) αβγ heterotrimer is a primary cellular energy sensor and central regulator of energy homeostasis. Activating skeletal muscle AMPK with small molecule drugs improves glucose uptake...
2.
Morrison K, Smiles W, Ling N, Hoque A, Shea G, Ngoei K, et al.
Cell Rep
. 2022 Feb;
38(7):110365.
PMID: 35172150
AMP-activated protein kinase (AMPK) and mechanistic target of rapamycin complex 1 (mTORC1) are metabolic kinases that co-ordinate nutrient supply with cell growth. AMPK negatively regulates mTORC1, and mTORC1 reciprocally phosphorylates...
3.
Loesch D, Kemp B, Bui M, Fisher P, Allan C, Sanislav O, et al.
Front Psychiatry
. 2021 Dec;
12:747268.
PMID: 34880790
Fragile X Associated Tremor/Ataxia Syndrome (FXTAS) is a neurodegenerative disorder affecting carriers of premutation alleles (PM) of the X-linked FMR1 gene, which contain CGG repeat expansions of 55-200 range in...
4.
Fisher P, Allan C, Sanislav O, Atkinson A, Ngoei K, Kemp B, et al.
Int J Mol Sci
. 2021 Oct;
22(19).
PMID: 34638732
The X-linked gene contains a non-coding trinucleotide repeat in its 5' region that, in normal, healthy individuals contains 20-44 copies. Large expansions of this region (>200 copies) cause fragile X...
5.
Langendorf C, OBrien M, Ngoei K, McAloon L, Dhagat U, Hoque A, et al.
J Biol Chem
. 2020 Sep;
295(48):16239-16250.
PMID: 32913128
The calcium-calmodulin-dependent protein kinase kinase-2 (CaMKK2) is a key regulator of cellular and whole-body energy metabolism. It is known to be activated by increases in intracellular Ca, but the mechanisms...
6.
Pinkosky S, Scott J, Desjardins E, Smith B, Day E, Ford R, et al.
Nat Metab
. 2020 Jul;
2(9):873-881.
PMID: 32719536
Long-chain fatty acids (LCFAs) play important roles in cellular energy metabolism, acting as both an important energy source and signalling molecules. LCFA-CoA esters promote their own oxidation by acting as...
7.
Lee J, Byun W, Kang M, Han J, Moon J, Shin M, et al.
FEBS J
. 2020 Mar;
287(10):2087-2104.
PMID: 32196931
Meteorin-like (metrnl) is a recently identified adipomyokine that beneficially affects glucose metabolism; however, its underlying mechanism of action is not completely understood. We here show that the level of metrnl...
8.
Ling N, Kaczmarek A, Hoque A, Davie E, Ngoei K, Morrison K, et al.
Nat Metab
. 2020 Jan;
2(1):41-49.
PMID: 31993556
Central to cellular metabolism and cell proliferation are highly conserved signalling pathways controlled by mammalian target of rapamycin (mTOR) and AMP-activated protein kinase (AMPK), dysregulation of which are implicated in...
9.
Lee H, Moon J, Chung I, Chung J, Park C, Lee J, et al.
FASEB J
. 2019 Nov;
33(12):14825-14840.
PMID: 31670977
ATPase inhibitory factor 1 (IF1) is an ATP synthase-interacting protein that suppresses the hydrolysis activity of ATP synthase. In this study, we observed that the expression of IF1 was up-regulated...
10.
Loesch D, Trost N, Bui M, Hammersley E, Lay S, Annesley S, et al.
Front Genet
. 2018 Nov;
9:531.
PMID: 30483310
The fragile X premutation (PM) allele contains a CGG expansion of 55-200 repeats in the gene's promoter. Male PM carriers have an elevated risk of developing neurological and psychiatric changes,...