John W Scott
Overview
Explore the profile of John W Scott including associated specialties, affiliations and a list of published articles.
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Articles
257
Citations
4939
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Recent Articles
1.
Smiles W, Ovens A, Yu D, Ling N, Poblete Goycoolea A, Morrison K, et al.
NPJ Metab Health Dis
. 2025 Mar;
3(1):8.
PMID: 40052110
The nutrient-sensitive protein kinases AMPK and mTORC1 form a fundamental negative feedback loop that governs cell growth and proliferation. mTORC1 phosphorylates α2-S345 in the AMPK αβγ heterotrimer to suppress its...
2.
Desjardins E, Day E, Scott J, Steinberg G
Methods Mol Biol
. 2025 Feb;
2882:121-137.
PMID: 39992507
Fatty acids are utilized to maintain cellular energy/adenine nucleotide balance under times of energetic stress such as during endurance exercise or fasting. It has long been recognized that fatty acids...
3.
Horne C, Dite T, Young S, Mather L, Dagley L, Johnson J, et al.
Proc Natl Acad Sci U S A
. 2025 Feb;
122(8):e2420961122.
PMID: 39964718
Protein Serine Kinase H1 (PSKH1) was recently identified as a crucial factor in kidney development and is overexpressed in prostate, lung, and kidney cancers. However, little is known about PSKH1...
4.
Dougherty J, Gerhardinger L, Johnson P, Regenbogen S, Scott J, Sangji N, et al.
J Trauma Acute Care Surg
. 2025 Feb;
PMID: 39956985
Background: Venous thromboembolism (VTE) is common after major injury. This elevated VTE risk likely continues beyond hospital discharge, but a lack of postdischarge surveillance limits our understanding of this complication...
5.
Dieleman J, Weil M, Beauchamp M, Bisignano C, Crosby S, DeJarnatt D, et al.
JAMA Health Forum
. 2025 Feb;
6(2):e245220.
PMID: 39951314
Importance: Understanding the drivers of health care spending across US counties is important for developing policies and assessing the allocation of health care services. Objective: To estimate the amount of...
6.
Dieleman J, Beauchamp M, Crosby S, DeJarnatt D, Johnson E, Lescinsky H, et al.
JAMA
. 2025 Feb;
PMID: 39951281
Importance: Understanding health conditions with the most spending and variation across locations and over time is important for identifying trends, highlighting inequalities, and developing strategies for lowering health spending. Objective:...
7.
Clark N, Hernandez A, Knowlton L, Stewart B, Bulger E, Malloy A, et al.
J Trauma Acute Care Surg
. 2025 Feb;
PMID: 39910712
Background: National estimates of financial hardship because of injury are lacking, which limits our ability to both define and mitigate the impacts of financial outcomes of trauma care. Furthermore, the...
8.
Fuller O, McLennan E, Egan C, Perera N, Terry L, Pyun J, et al.
iScience
. 2025 Feb;
28(2):111752.
PMID: 39898049
Exercise improves cognitive function in Alzheimer's disease (AD) via mechanism that are not fully clear. Here, we first examined the effect of voluntary exercise training (VET) on energy metabolism and...
9.
Fuller O, Egan C, Robinson T, Perera N, Latchman H, Terry L, et al.
Life Metab
. 2025 Jan;
3(1):load043.
PMID: 39871877
Obesity has been linked to a range of pathologies, including dementia. In contrast, regular physical activity is associated with the prevention or reduced progression of neurodegeneration. Specifically, physical activity can...
10.
Clark N, Hernandez A, Bertalan M, Wang V, Greenberg S, Ibrahim A, et al.
JAMA Netw Open
. 2025 Jan;
8(1):e2455258.
PMID: 39836423
Importance: Timely access to care is a key metric for health care systems and is particularly important in conditions that acutely worsen with delays in care, including surgical emergencies. However,...