Kevin E Conley
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Explore the profile of Kevin E Conley including associated specialties, affiliations and a list of published articles.
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47
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1711
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Recent Articles
1.
Roshanravan B, Liu S, Ali A, Shankland E, Goss C, Amory J, et al.
PLoS One
. 2021 Jul;
16(7):e0253849.
PMID: 34264994
Background: Loss of mitochondrial function contributes to fatigue, exercise intolerance and muscle weakness, and is a key factor in the disability that develops with age and a wide variety of...
2.
Liu S, Valencia A, VanDoren M, Shankland E, Roshanravan B, Conley K, et al.
Physiol Rep
. 2021 Jun;
9(11):e14887.
PMID: 34110707
Endurance training (ET) is recommended for the elderly to improve metabolic health and aerobic capacity. However, ET-induced adaptations may be suboptimal due to oxidative stress and exaggerated inflammatory response to...
3.
Whitson J, Bitto A, Zhang H, Sweetwyne M, Coig R, Bhayana S, et al.
Aging Cell
. 2020 Aug;
19(10):e13213.
PMID: 32779818
The effects of two different mitochondrial-targeted drugs, SS-31 and NMN, were tested on Old mouse hearts. After treatment with the drugs, individually or Combined, heart function was examined by echocardiography....
4.
Johannsen D, Marlatt K, Conley K, Smith S, Ravussin E
Am J Clin Nutr
. 2019 Jun;
110(4):805-813.
PMID: 31204775
Background: A metabolic adaptation, defined as an increase in energy expenditure (EE) beyond what is expected with weight gain during overfeeding (OF), has been reported but also refuted. Much of...
5.
Liu S, Ali A, Campbell M, Kilroy K, Shankland E, Roshanravan B, et al.
J Cachexia Sarcopenia Muscle
. 2018 Sep;
9(5):826-833.
PMID: 30259703
Background: Building both strength and endurance has been a challenge in exercise training in the elderly, but dietary supplements hold promise as agents for improving muscle adaptation. Here, we test...
6.
Toledo F, Johannsen D, Covington J, Bajpeyi S, Goodpaster B, Conley K, et al.
Diabetologia
. 2017 Nov;
61(2):466-475.
PMID: 29150696
Aims/hypotheses: Reduced mitochondrial capacity in skeletal muscle has been observed in obesity and type 2 diabetes. In humans, the aetiology of this abnormality is not well understood but the possibility...
7.
Mischley L, Conley K, Shankland E, Kavanagh T, Rosenfeld M, Duda J, et al.
NPJ Parkinsons Dis
. 2017 Jul;
2:16002.
PMID: 28725693
Glutathione (GSH) is depleted early in the course of Parkinson's disease (PD), and deficiency has been shown to perpetuate oxidative stress, mitochondrial dysfunction, impaired autophagy, and cell death. GSH repletion...
8.
Bajpeyi S, Pasarica M, Conley K, Newcomer B, Jubrias S, Gamboa C, et al.
Metabolism
. 2017 Mar;
69:24-32.
PMID: 28285649
Aims: Pioglitazone (Pio) is known to improve insulin sensitivity in skeletal muscle. However, the role of Pio in skeletal muscle lipid metabolism and skeletal muscle oxidative capacity is not clear....
9.
Ryu D, Zhang H, Ropelle E, Sorrentino V, Mazala D, Mouchiroud L, et al.
Sci Transl Med
. 2016 Nov;
8(361):361ra139.
PMID: 27798264
Neuromuscular diseases are often caused by inherited mutations that lead to progressive skeletal muscle weakness and degeneration. In diverse populations of normal healthy mice, we observed correlations between the abundance...
10.
Sparks L, Redman L, Conley K, Harper M, Yi F, Hodges A, et al.
J Clin Endocrinol Metab
. 2016 Oct;
102(1):111-121.
PMID: 27778643
Context: The effects of caloric restriction (CR) on in vivo muscle mitochondrial function in humans are controversial. Objective: We evaluated muscle mitochondrial function and associated transcriptional profiles in nonobese humans...