Eric G Shankland
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Explore the profile of Eric G Shankland including associated specialties, affiliations and a list of published articles.
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18
Citations
468
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Recent Articles
1.
Kramer P, Coen P, Cawthon P, Distefano G, Cummings S, Goodpaster B, et al.
J Gerontol A Biol Sci Med Sci
. 2023 Dec;
79(4).
PMID: 38150179
The age-related decline in muscle mitochondrial energetics contributes to the loss of mobility in older adults. Women experience a higher prevalence of mobility impairment compared to men, but it is...
2.
Kramer P, Coen P, Cawthon P, Distefano G, Cummings S, Goodpaster B, et al.
medRxiv
. 2023 Nov;
PMID: 37987007
The age-related decline in muscle mitochondrial energetics contributes to the loss of mobility in older adults. Women experience a higher prevalence of mobility impairment compared to men, but it is...
3.
Cummings S, Newman A, Coen P, Hepple R, Collins R, Kennedy Ms K, et al.
J Gerontol A Biol Sci Med Sci
. 2023 Feb;
78(11):2083-2093.
PMID: 36754371
Background: The Study of Muscle, Mobility and Aging (SOMMA) aims to understand the biological basis of many facets of human aging, with a focus on mobility decline, by creating a...
4.
Mau T, Lui L, Distefano G, Kramer P, Ramos S, Toledo F, et al.
J Gerontol A Biol Sci Med Sci
. 2022 Dec;
78(8):1367-1375.
PMID: 36462195
Background: Mitochondrial energetics are an important property of aging muscle, as generation of energy is pivotal to the execution of muscle contraction. However, its association with functional outcomes, including leg...
5.
Roshanravan B, Liu S, Ali A, Shankland E, Goss C, Amory J, et al.
PLoS One
. 2021 Jul;
16(7):e0253849.
PMID: 34264994
Background: Loss of mitochondrial function contributes to fatigue, exercise intolerance and muscle weakness, and is a key factor in the disability that develops with age and a wide variety of...
6.
Liu S, Valencia A, VanDoren M, Shankland E, Roshanravan B, Conley K, et al.
Physiol Rep
. 2021 Jun;
9(11):e14887.
PMID: 34110707
Endurance training (ET) is recommended for the elderly to improve metabolic health and aerobic capacity. However, ET-induced adaptations may be suboptimal due to oxidative stress and exaggerated inflammatory response to...
7.
Whitson J, Bitto A, Zhang H, Sweetwyne M, Coig R, Bhayana S, et al.
Aging Cell
. 2020 Aug;
19(10):e13213.
PMID: 32779818
The effects of two different mitochondrial-targeted drugs, SS-31 and NMN, were tested on Old mouse hearts. After treatment with the drugs, individually or Combined, heart function was examined by echocardiography....
8.
Liu S, Ali A, Campbell M, Kilroy K, Shankland E, Roshanravan B, et al.
J Cachexia Sarcopenia Muscle
. 2018 Sep;
9(5):826-833.
PMID: 30259703
Background: Building both strength and endurance has been a challenge in exercise training in the elderly, but dietary supplements hold promise as agents for improving muscle adaptation. Here, we test...
9.
Mischley L, Conley K, Shankland E, Kavanagh T, Rosenfeld M, Duda J, et al.
NPJ Parkinsons Dis
. 2017 Jul;
2:16002.
PMID: 28725693
Glutathione (GSH) is depleted early in the course of Parkinson's disease (PD), and deficiency has been shown to perpetuate oxidative stress, mitochondrial dysfunction, impaired autophagy, and cell death. GSH repletion...
10.
Mischley L, Lau R, Shankland E, Wilbur T, Padowski J
J Parkinsons Dis
. 2017 Apr;
7(2):289-299.
PMID: 28436395
Background: Reduced glutathione (GSH) is an endogenously synthesized tripeptide depleted early in the course of Parkinson's disease (PD) and GSH augmentation has been proposed as a therapeutic strategy in PD....