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Kermit L Carraway 3rd

Explore the profile of Kermit L Carraway 3rd including associated specialties, affiliations and a list of published articles. Areas
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Articles 56
Citations 1719
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Recent Articles
1.
Hu M, Liu R, Castro N, Loza Sanchez L, Rueankham L, Learn J, et al.
Sci Rep . 2024 Aug; 14(1):20263. PMID: 39217266
Derivatives of the potassium-sparing diuretic amiloride are preferentially cytotoxic toward tumor cells relative to normal cells, and have the capacity to target tumor cell populations resistant to currently employed therapeutic...
2.
Freeland J, Munoz M, ODonnell 3rd E, Langerman J, Darrow M, Bergonio J, et al.
Clin Cancer Res . 2024 Aug; 30(21):4957-4973. PMID: 39177582
Purpose: High-grade complex karyotype sarcomas are a heterogeneous group of tumors with a uniformly poor prognosis. Within complex karyotype sarcomas, there are innumerable genetic changes but identifying those that are...
3.
Dreyer C, VanderVorst K, Natwick D, Bell G, Sood P, Hernandez M, et al.
Cancer Lett . 2023 Jun; 567:216280. PMID: 37336284
Targeting common oncogenic drivers of glioblastoma multiforme (GBM) in patients has remained largely ineffective, raising the possibility that alternative pathways may contribute to tumor aggressiveness. Here we demonstrate that Vangl1...
4.
VanderVorst K, Dreyer C, Hatakeyama J, Bell G, Learn J, Berg A, et al.
Breast Cancer Res . 2023 May; 25(1):52. PMID: 37147680
Background: In light of the growing appreciation for the role of collective cell motility in metastasis, a deeper understanding of the underlying signaling pathways will be critical to translating these...
5.
Konopelski Snavely S, Srinivasan S, Dreyer C, Tan J, Carraway 3rd K, Henry Ho H
Curr Top Dev Biol . 2023 Mar; 153:195-227. PMID: 36967195
Deciphering non-canonical WNT signaling has proven to be both fascinating and challenging. Discovered almost 30 years ago, non-canonical WNT ligands signal independently of the transcriptional co-activator β-catenin to regulate a...
6.
Berg A, Showalter M, Kosaisawe N, Hu M, Stephens N, Sa M, et al.
Cancer Lett . 2023 Feb; 557:216090. PMID: 36773796
Bis(monoacylglycero)phosphates (BMPs), a class of lipids highly enriched within endolysosomal organelles, are key components of the lysosomal intraluminal vesicles responsible for activating sphingolipid catabolic enzymes. While BMPs are understudied relative...
7.
Srinivasan S, Regmi R, Lin X, Dreyer C, Chen X, Quinn S, et al.
Nat Commun . 2022 Jul; 13(1):3709. PMID: 35794108
Single pass cell surface receptors regulate cellular processes by transmitting ligand-encoded signals across the plasma membrane via changes to their extracellular and intracellular conformations. This transmembrane signaling is generally initiated...
8.
Dreyer C, VanderVorst K, Carraway 3rd K
Front Cell Dev Biol . 2022 Jun; 10:887100. PMID: 35646914
The establishment of polarity within tissues and dynamic cellular morphogenetic events are features common to both developing and adult tissues, and breakdown of these programs is associated with diverse human...
9.
Berg A, Rowson-Hodel A, Hu M, Keeling M, Wu H, VanderVorst K, et al.
Cancers (Basel) . 2022 Feb; 14(4). PMID: 35205696
The resistance of cancer cell subpopulations, including cancer stem cell (CSC) populations, to apoptosis-inducing chemotherapeutic agents is a key barrier to improved outcomes for cancer patients. The cationic amphiphilic drug...
10.
Hu M, Carraway 3rd K
Front Oncol . 2021 Jan; 10:605361. PMID: 33425762
A major confounding issue in the successful treatment of cancer is the existence of tumor cell populations that resist therapeutic agents and regimens. While tremendous effort has gone into understanding...