Kendall A Curtis
Overview
Explore the profile of Kendall A Curtis including associated specialties, affiliations and a list of published articles.
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8
Citations
171
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Recent Articles
1.
Ng B, Tasaki S, Greathouse K, Walker C, Zhang A, Covitz S, et al.
Nat Neurosci
. 2024 Nov;
27(11):2240-2252.
PMID: 39482360
Brain connectivity arises from interactions across biophysical scales, ranging from molecular to cellular to anatomical to network level. To date, there has been little progress toward integrated analysis across these...
2.
Curtis K, Kunkhyen T, Cheetham C
Methods Mol Biol
. 2024 Oct;
2861:97-109.
PMID: 39395100
Two-photon microscopy enables imaging of calcium signaling at cellular or subcellular resolution up to hundreds of microns deep in the living brain. Changes in the brightness of fluorescent calcium indicators...
3.
Walker C, Liu E, Greathouse K, Adamson A, Wilson J, Poovey E, et al.
Sci Adv
. 2024 Aug;
10(32):eadn5181.
PMID: 39110801
Episodic memory in older adults is varied and perceived to rely on numbers of synapses or dendritic spines. We analyzed 2157 neurons among 128 older individuals from the Religious Orders...
4.
Ng B, Tasaki S, Greathouse K, Walker C, Zhang A, Covitz S, et al.
bioRxiv
. 2023 Aug;
PMID: 37546752
One-sentence Summary: Dendritic spine morphometry and synaptic proteins unite the divergent fields of molecular biology and neuroimaging.
5.
Walker C, Greathouse K, Tuscher J, Dammer E, Weber A, Liu E, et al.
J Neurosci
. 2023 Apr;
43(20):3764-3785.
PMID: 37055180
Proteomic studies using postmortem human brain tissue samples have yielded robust assessments of the aging and neurodegenerative disease(s) proteomes. While these analyses provide lists of molecular alterations in human conditions,...
6.
Henderson B, Greathouse K, Ramdas R, Walker C, Rao T, Bach S, et al.
Sci Signal
. 2019 Jun;
12(587).
PMID: 31239325
Alzheimer's disease (AD) therapies predominantly focus on β-amyloid (Aβ), but Aβ effects may be maximal before clinical symptoms appear. Downstream of Aβ, dendritic spine loss correlates most strongly with cognitive...
7.
Greathouse K, Boros B, Deslauriers J, Henderson B, Curtis K, Gentry E, et al.
Brain Struct Funct
. 2018 Sep;
223(9):4227-4241.
PMID: 30196430
Rho-associated protein kinases (ROCK) 1 and 2 are attractive drug targets for a range of neurologic disorders; however, a critical barrier to ROCK-based therapeutics is ambiguity over whether there are...
8.
Boros B, Greathouse K, Gentry E, Curtis K, Birchall E, Gearing M, et al.
Ann Neurol
. 2017 Sep;
82(4):602-614.
PMID: 28921611
Objective: Neuroimaging and other biomarker assays suggest that the pathological processes of Alzheimer's disease (AD) begin years prior to clinical dementia onset. However, some 30 to 50% of older individuals...