Audrey J Weber
Overview
Explore the profile of Audrey J Weber including associated specialties, affiliations and a list of published articles.
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6
Citations
30
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Recent Articles
1.
Ng B, Tasaki S, Greathouse K, Walker C, Zhang A, Covitz S, et al.
Nat Neurosci
. 2024 Nov;
27(11):2240-2252.
PMID: 39482360
Brain connectivity arises from interactions across biophysical scales, ranging from molecular to cellular to anatomical to network level. To date, there has been little progress toward integrated analysis across these...
2.
Walker C, Liu E, Greathouse K, Adamson A, Wilson J, Poovey E, et al.
Sci Adv
. 2024 Aug;
10(32):eadn5181.
PMID: 39110801
Episodic memory in older adults is varied and perceived to rely on numbers of synapses or dendritic spines. We analyzed 2157 neurons among 128 older individuals from the Religious Orders...
3.
Cook A, Greathouse K, Manuel P, Cooper N, Eberhardt J, Freeman C, et al.
Mol Brain
. 2024 Jun;
17(1):33.
PMID: 38840181
Loss-of-function mutations in the progranulin (GRN) gene are an autosomal dominant cause of Frontotemporal Dementia (FTD). These mutations typically result in haploinsufficiency of the progranulin protein. Grn mice provide a...
4.
Walker C, Greathouse K, Tuscher J, Dammer E, Weber A, Liu E, et al.
J Neurosci
. 2023 Apr;
43(20):3764-3785.
PMID: 37055180
Proteomic studies using postmortem human brain tissue samples have yielded robust assessments of the aging and neurodegenerative disease(s) proteomes. While these analyses provide lists of molecular alterations in human conditions,...
5.
Weber A, Adamson A, Greathouse K, Andrade J, Freeman C, Seo J, et al.
Mol Brain
. 2021 Nov;
14(1):169.
PMID: 34794469
Rho-associated kinase isoform 2 (ROCK2) is an attractive drug target for several neurologic disorders. A critical barrier to ROCK2-based research and therapeutics is the lack of a mouse model that...
6.
Weber A, Herskowitz J
Front Cell Neurosci
. 2021 Apr;
15:636017.
PMID: 33790742
Rho-associated coiled-coil containing kinase isoform 2 (ROCK2) is a member of the AGC family of serine/threonine kinases and an extensively studied regulator of actin-mediated cytoskeleton contractility. Over the past decade,...