Kelvin W Li
Overview
Explore the profile of Kelvin W Li including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
20
Citations
752
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Tang Q, Leung J, Peng Y, Sanchez-Fueyo A, Lozano J, Lam A, et al.
Sci Transl Med
. 2022 Nov;
14(669):eabo2628.
PMID: 36322627
Promoting immune tolerance to transplanted organs can minimize the amount of immunosuppressive drugs that patients need to take, reducing lifetime risks of mortality and morbidity. Regulatory T cells (T) are...
2.
Lawitz E, Li K, Nyangau E, Field T, Chuang J, Billin A, et al.
J Lipid Res
. 2022 Jul;
63(9):100250.
PMID: 35835205
De novo lipogenesis (DNL) converts carbon substrates to lipids. Increased hepatic DNL could contribute to pathogenic liver triglyceride accumulation in nonalcoholic steatohepatitis (NASH) and therefore may be a potential target...
3.
Cohen C, Li K, Alazraki A, Beysen C, Carrier C, Cleeton R, et al.
J Clin Invest
. 2021 Dec;
131(24).
PMID: 34907907
BACKGROUNDHepatic de novo lipogenesis (DNL) is elevated in nonalcoholic fatty liver disease (NAFLD). Improvements in hepatic fat by dietary sugar reduction may be mediated by reduced DNL, but data are...
4.
Zarnitsyna V, Akondy R, Ahmed H, McGuire D, Zarnitsyn V, Moore M, et al.
PLoS Comput Biol
. 2021 Oct;
17(10):e1009468.
PMID: 34648489
Understanding how immunological memory lasts a lifetime requires quantifying changes in the number of memory cells as well as how their division and death rates change over time. We address...
5.
Kelly K, Reagan W, Sonnenberg G, Clasquin M, Hales K, Asano S, et al.
Nat Metab
. 2020 Sep;
2(10):1163-1178.
PMID: 32929234
Acetyl-CoA carboxylase (ACC) catalyses the first step of de novo lipogenesis (DNL). Pharmacologic inhibition of ACC has been of interest for therapeutic intervention in a wide range of diseases. We...
6.
Loomba R, Decaris M, Li K, Shankaran M, Mohammed H, Matthews M, et al.
Clin Infect Dis
. 2018 Dec;
69(3):542-545.
PMID: 30590481
In a pilot study, heavy water labeling was used to determine hepatitis B surface antigen (HBsAg) turnover rates in chronic hepatitis B (CHB) patients. The mean (standard deviation) half-life of...
7.
Akondy R, Fitch M, Edupuganti S, Yang S, Kissick H, Li K, et al.
Nature
. 2017 Dec;
552(7685):362-367.
PMID: 29236685
The differentiation of human memory CD8 T cells is not well understood. Here we address this issue using the live yellow fever virus (YFV) vaccine, which induces long-term immunity in...
8.
Carson R, Lewis C, Erickson M, Zagieboylo A, Naylor B, Li K, et al.
J Lipid Res
. 2017 Jul;
58(9):1884-1892.
PMID: 28743728
Compartmentalization of metabolism into specific regions of the cell, tissue, and organ is critical to life for all organisms. Mass spectrometric imaging techniques have been valuable in identifying and quantifying...
9.
Burger J, Li K, Keating M, Sivina M, Amer A, Garg N, et al.
JCI Insight
. 2017 Feb;
2(2):e89904.
PMID: 28138560
Ibrutinib is an effective targeted therapy for patients with chronic lymphocytic leukemia (CLL) that inhibits Bruton's tyrosine kinase (BTK), a kinase involved in B cell receptor signaling. We used stable...
10.
Decaris M, Li K, Emson C, Gatmaitan M, Liu S, Wang Y, et al.
Hepatology
. 2016 Oct;
65(1):78-88.
PMID: 27706836
Conclusion: Using a well-characterized cohort of patients with biopsy-proven NAFLD, this study demonstrates that hepatic scar in NASH is actively remodeled even in advanced fibrosis, a disease that is generally...