Kellen J Cavagnero
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Explore the profile of Kellen J Cavagnero including associated specialties, affiliations and a list of published articles.
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16
Citations
181
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Recent Articles
1.
Cavagnero K, Albright J, Li F, Dokoshi T, Bogle R, Kirma J, et al.
bioRxiv
. 2024 Jul;
PMID: 38979312
Sweet's syndrome is a poorly understood inflammatory skin disease characterized by neutrophil infiltration to the dermis. Single-nucleus and bulk transcriptomics of archival clinical samples of Sweet's syndrome revealed a prominent...
2.
Dokoshi T, Chen Y, Cavagnero K, Rahman G, Hakim D, Brinton S, et al.
Nat Commun
. 2024 Apr;
15(1):3009.
PMID: 38589392
The composition of the microbial community in the intestine may influence the functions of distant organs such as the brain, lung, and skin. These microbes can promote disease or have...
3.
Cavagnero K, Li F, Dokoshi T, Nakatsuji T, ONeill A, Aguilera C, et al.
J Exp Med
. 2024 Feb;
221(4).
PMID: 38393304
The skin provides an essential barrier for host defense through rapid action of multiple resident and recruited cell types, but the complex communication network governing these processes is incompletely understood....
4.
Khalil S, Cavagnero K, Williams M, ONeill A, Nakatsuji T, Gallo R
J Invest Dermatol
. 2023 Aug;
144(1):84-95.e3.
PMID: 37544587
Absorption of dietary iron is largely regulated by the liver hormone hepcidin, which is released under conditions of iron overload and inflammation. Although hepcidin-dependent regulation of iron uptake and circulation...
5.
ONeill A, Cavagnero K, Seidman J, Zaramela L, Chen Y, Li F, et al.
J Invest Dermatol
. 2023 Jul;
144(1):116-124.e4.
PMID: 37478901
Cutibacterium acnes is a commensal bacterium on the skin that is generally well-tolerated, but different strain types have been hypothesized to contribute to the disease acne vulgaris. To understand how...
6.
Nakatsuji T, Brinton S, Cavagnero K, ONeill A, Chen Y, Dokoshi T, et al.
Cell Rep
. 2023 May;
42(5):112494.
PMID: 37167061
During inflammation, the skin deploys antimicrobial peptides (AMPs) yet during allergic inflammation it becomes more susceptible to Staphylococcus aureus. To understand this contradiction, single-cell sequencing of Il4ra mice combined with...
7.
8.
Cavagnero K, Gallo R
Front Immunol
. 2023 Jan;
13:1058862.
PMID: 36591258
The term fibroblast has been used generally to describe spindle-shaped stromal cells of mesenchymal origin that produce extracellular matrix, establish tissue structure, and form scar. Current evidence has found that...
9.
ONeill A, Liggins M, Seidman J, Do T, Li F, Cavagnero K, et al.
Sci Transl Med
. 2022 Feb;
14(632):eabh1478.
PMID: 35171653
Innate immune defense against deep tissue infection by is orchestrated by fibroblasts that become antimicrobial when triggered to differentiate into adipocytes. However, the role of this process in noninfectious human...
10.
Dokoshi T, Seidman J, Cavagnero K, Li F, Liggins M, Taylor B, et al.
J Clin Invest
. 2021 Nov;
131(21).
PMID: 34720087
Inflammatory disorders of the skin are frequently associated with inflammatory bowel diseases (IBDs). To explore mechanisms by which these organs communicate, we performed single-cell RNA-Seq analysis on fibroblasts from humans...