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Taylor A Doherty

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Articles 71
Citations 2373
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Recent Articles
1.
Aguilar D, Zhu F, Millet A, Millet N, Germano P, Pisegna J, et al.
Nat Commun . 2024 Oct; 15(1):8914. PMID: 39414787
Sensory neurons sense pathogenic infiltration to drive innate immune responses, but their role in humoral immunity is unclear. Here, using mouse models of Streptococcus pneumoniae infection and Alternaria alternata asthma,...
2.
Huang Y, Wang X, Kim J, Yao X, Sethi A, Strohm A, et al.
Sci Rep . 2024 Aug; 14(1):20167. PMID: 39215111
Innate lymphoid cells (ILCs) are a heterogeneous population that play diverse roles in airway inflammation after exposure to allergens and infections. However, how ILCs respond after exposure to environmental toxins...
3.
Huang Y, Wang X, Kim J, Yao X, Sethi A, Strohm A, et al.
bioRxiv . 2024 Jul; PMID: 38979234
Innate lymphoid cells (ILCs) are a heterogeneous population that play diverse roles in airway inflammation after exposure to allergens and infections. However, how ILCs respond after exposure to environmental toxins...
4.
Aguilar D, Zhu F, Millet A, Millet N, Germano P, Pisegna J, et al.
bioRxiv . 2024 Jan; PMID: 38260709
Sensory neurons sense pathogenic infiltration, serving to inform immune coordination of host defense. However, sensory neuron-immune interactions have been predominantly shown to drive innate immune responses. Humoral memory, whether protective...
5.
Han H, Choi Y, Hong H, Kim C, Byun M, Cho J, et al.
Life Sci . 2023 Oct; 334:122163. PMID: 37890698
Aims: Despite recent investigations on the role of chitinase in asthma, its role in obesity-induced asthma has not been evaluated. Therefore, we investigated the roles of chitin, chitinase-1, and a...
6.
Jang S, Pak K, Strom A, Gomez L, Kim K, Doherty T, et al.
Int Forum Allergy Rhinol . 2023 Sep; 14(4):786-793. PMID: 37676246
Introduction: While localized inflammation has been implicated in the pathophysiology of acute coronavirus disease of 2019 (COVID-19) olfactory dysfunction (OD), persistent COVID-19 OD remains poorly understood with limited therapeutics. Our...
7.
Badrani J, Cavagnero K, Eastman J, Kim A, Strohm A, Yan C, et al.
J Allergy Clin Immunol . 2023 Aug; 152(5):1330-1335.e1. PMID: 37543185
Background: Aspirin-exacerbated respiratory disease (AERD) is associated with high levels of cysteinyl leukotrienes, prostaglandin D, and low levels of prostaglandin E. Further, 15-hydroxyeicosatetraenoic acid (15-HETE) levels may have predictive value...
8.
Badrani J, Strohm A, Haung Y, Doherty T
Bio Protoc . 2023 Jul; 13(14):e4717. PMID: 37497449
Innate lymphoid cells (ILCs) are a rare cell population subdivided into ILC1s, ILC2s, and ILC3s, based on transcription factor expression and cytokine production. In models of lung inflammation, the release...
9.
Wang X, Doherty T, James C
Ann Allergy Asthma Immunol . 2023 Jun; 131(6):720-725. PMID: 37343826
Millions of veterans have been exposed to burn pit smoke during combat deployments throughout the last three decades. Toxic compounds present in burn pit fumes that may cause or exacerbate...
10.
Smith T, Doherty T
Cell Rep Med . 2023 May; 4(5):101040. PMID: 37196636
In an era of rapid identification of inborn errors of immunity, Sharma et al. report novel heterozygous gain-of-function variants in the signal transducer and activator of transcription 6 (STAT6) gene...