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Keith R Loeb

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Recent Articles
21.
Zheng G, Terry J, Belgrader P, Ryvkin P, Bent Z, Wilson R, et al.
Nat Commun . 2017 Jan; 8:14049. PMID: 28091601
Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3' mRNA counting of tens of thousands of single cells...
22.
Bleakley M, Heimfeld S, Loeb K, Jones L, Chaney C, Seropian S, et al.
J Clin Invest . 2015 Jun; 125(7):2677-89. PMID: 26053664
Background: Graft-versus-host disease (GVHD) is a major cause of morbidity and mortality following allogeneic hematopoietic stem cell transplantation (HCT). In mice, naive T cells (TN) cause more severe GVHD than...
23.
Loeb K, Cherian S, Becker P, Walter R, Pagel J, Abkowitz J, et al.
Br J Haematol . 2015 May; 172(1):134-6. PMID: 26010105
No abstract available.
24.
Zhang M, Churpek J, Keel S, Walsh T, Lee M, Loeb K, et al.
Nat Genet . 2015 Jan; 47(2):180-5. PMID: 25581430
We report germline missense mutations in ETV6 segregating with the dominant transmission of thrombocytopenia and hematologic malignancy in three unrelated kindreds, defining a new hereditary syndrome featuring thrombocytopenia with susceptibility...
25.
Bar M, Tong W, Othus M, Loeb K, Estey E
Biol Blood Marrow Transplant . 2014 Dec; 21(3):546-51. PMID: 25545726
Knowledge regarding the rate of central nervous system (CNS) involvement and risk factors for its development in acute myeloid leukemia (AML) patients undergoing allogeneic hematopoietic cell transplantation (HCT) are limited....
26.
Evans A, Loeb K, Shulman H, Hassan S, Qiu W, Hockenbery D, et al.
Am J Surg Pathol . 2014 Dec; 39(2):212-20. PMID: 25517948
Development of liver disease after hematopoietic cell transplantation is common and the causes diverse. Infection by hepatitis C virus (HCV) can be seen in patients who are chronically infected before...
27.
Beer P, Knapp D, Miller P, Kannan N, Sloma I, Heel K, et al.
Blood . 2014 Nov; 125(3):504-15. PMID: 25370416
Without effective therapy, chronic-phase chronic myeloid leukemia (CP-CML) evolves into an acute leukemia (blast crisis [BC]) that displays either myeloid or B-lymphoid characteristics. This transition is often preceded by a...
28.
Noble M, Kuhr C, Graves S, Loeb K, Sun S, Keilman G, et al.
Mol Ther . 2013 Jun; 21(9):1687-94. PMID: 23732985
Ultrasound (US) was applied to a targeted canine liver lobe simultaneously with injection of plasmid DNA (pDNA)/microbubble (MB) complexes into a portal vein (PV) segmental branch and occlusion of the...
29.
Foss E, Radulovic D, Stirewalt D, Radich J, Sala-Torra O, Pogosova-Agadjanyan E, et al.
J Proteome Res . 2012 Aug; 11(10):5005-10. PMID: 22900933
Despite immense interest in the proteome as a source of biomarkers in cancer, mass spectrometry has yet to yield a clinically useful protein biomarker for tumor classification. To explore the...
30.
Loeb K, Asgari M, Hawes S, Feng Q, Stern J, Jiang M, et al.
PLoS One . 2012 May; 7(4):e34422. PMID: 22545084
Background: Non-melanoma skin cancers are one of the most common human malignancies accounting for 2-3% of tumors in the US and represent a significant health burden. Epidemiology studies have implicated...