Keith Ashman
Overview
Explore the profile of Keith Ashman including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
1540
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Recent Articles
11.
Salomon C, Ryan J, Sobrevia L, Kobayashi M, Ashman K, Mitchell M, et al.
PLoS One
. 2013 Jul;
8(7):e68451.
PMID: 23861904
Vasculogenesis and angiogenesis are critical processes in fetal circulation and placental vasculature development. Placental mesenchymal stem cells (pMSC) are known to release paracrine factors (some of which are contained within...
12.
Cuello S, Ximenez-Embun P, Ruppen I, Schonthaler H, Ashman K, Madrid Y, et al.
Analyst
. 2012 Sep;
137(22):5302-11.
PMID: 23014190
Mercury toxicity and its implications in development are a major concern, due to the major threat to ecosystems and human health that this compound represents. Although some of the effects...
13.
Ruppen-Canas I, Lopez-Casas P, Garcia F, Ximenez-Embun P, Munoz M, Morelli M, et al.
Proteomics
. 2012 May;
12(9):1319-27.
PMID: 22589181
New disease specific biomarkers, especially for cancer, are urgently needed to improve individual diagnosis, prognosis, and treatment selection, that is, for personalized medicine. Genetic mutations that affect protein function drive...
14.
Ezkurdia I, Del Pozo A, Frankish A, Rodriguez J, Harrow J, Ashman K, et al.
Mol Biol Evol
. 2012 Mar;
29(9):2265-83.
PMID: 22446687
Advances in high-throughput mass spectrometry are making proteomics an increasingly important tool in genome annotation projects. Peptides detected in mass spectrometry experiments can be used to validate gene models and...
15.
Ruppen I, Grau L, Orenes-Pinero E, Ashman K, Gil M, Algaba F, et al.
Mol Cell Proteomics
. 2010 Feb;
9(10):2276-91.
PMID: 20139371
KiSS-1 is a metastasis suppressor gene reported to be involved in the progression of several solid neoplasias. The loss of KiSS-1 gene expression has been shown to be inversely correlated...
16.
Sherman J, McKay M, Ashman K, Molloy M
Mol Cell Proteomics
. 2009 Jun;
8(9):2051-62.
PMID: 19556279
The growing use of selected reaction monitoring (SRM) mass spectrometry in proteomic analyses led us to investigate how to identify peptides by SRM using only a minimal number of fragment...
17.
Ashman K, Lopez Villar E
Clin Transl Oncol
. 2009 Jun;
11(6):356-62.
PMID: 19531450
Protein phosphorylation plays key roles in the regulation of normal and cancer cells. It is a highly dynamic process. Protein kinases are the targets of several new cancer drugs and...
18.
Metalnikov P, ODonnel P, Vassilovski G, Ashman K
J Biomol Tech
. 2009 Jun;
13(2):49-55.
PMID: 19498966
The development of robotic sample preparation systems has allowed the throughput of protein analysis to be accelerated. However, one of the rate-limiting steps in preparing protein samples for analysis by...
19.
Sherman J, McKay M, Ashman K, Molloy M
Proteomics
. 2009 Mar;
9(5):1120-3.
PMID: 19253278
Selected reaction monitoring (SRM) MS is proving to be a popular approach for targeted quantitative proteomics. The use of proteotypic peptides as candidates for SRM analysis is a wise first...
20.
Erwin W, Ashman K, ODonnel P, Inman R
Arthritis Rheum
. 2006 Dec;
54(12):3859-67.
PMID: 17136753
Objective: To identify the components of conditioned medium obtained from intervertebral disc nucleus pulposus-derived canine notochord cells, and to evaluate the capacity of such factors to affect disc-derived chondrocyte gene...