Dylan Xavier
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Explore the profile of Dylan Xavier including associated specialties, affiliations and a list of published articles.
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10
Citations
161
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Recent Articles
1.
Jackson C, Liu J, Liu H, Williams S, Anees A, Noor Z, et al.
Cancer Res Commun
. 2025 Feb;
PMID: 40014866
Although HPV-positive OPSCC is associated with better prognosis than HPV-negative disease, ~30% of cases relapse despite curative-intent radiotherapy (+/- chemotherapy). We aimed to develop a proteomic signature associated with risk...
2.
Humphries E, Xavier D, Ashman K, Hains P, Robinson P
J Proteome Res
. 2024 May;
23(7):2355-2366.
PMID: 38819404
High-throughput tissue proteomics has great potential in the advancement of precision medicine. Here, we investigated the combined sensitivity of trap-elute microflow liquid chromatography with a ZenoTOF for DIA proteomics and...
3.
Xavier D, Lucas N, Williams S, Koh J, Ashman K, Loudon C, et al.
Anal Chem
. 2024 Mar;
96(10):4093-4102.
PMID: 38427620
Proteomic analysis by mass spectrometry of small (≤2 mg) solid tissue samples from diverse formats requires high throughput and comprehensive proteome coverage. We developed a nearly universal, rapid, and robust...
4.
Goncalves E, Poulos R, Cai Z, Barthorpe S, Manda S, Lucas N, et al.
Cancer Cell
. 2022 Jul;
40(8):835-849.e8.
PMID: 35839778
The proteome provides unique insights into disease biology beyond the genome and transcriptome. A lack of large proteomic datasets has restricted the identification of new cancer biomarkers. Here, proteomes of...
5.
Poulos R, Hains P, Shah R, Lucas N, Xavier D, Manda S, et al.
Nat Commun
. 2020 Aug;
11(1):3793.
PMID: 32732981
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop...
6.
Lucas N, Robinson A, Marcker Espersen M, Mahboob S, Xavier D, Xue J, et al.
J Proteome Res
. 2018 Nov;
18(1):399-405.
PMID: 30444966
We have developed a streamlined proteomic sample preparation protocol termed Accelerated Barocycler Lysis and Extraction (ABLE) that substantially reduces the time and cost of tissue sample processing. ABLE is based...
7.
Jones J, Mirzaei M, Ravishankar P, Xavier D, Lim D, Shin D, et al.
Philos Trans A Math Phys Eng Sci
. 2016 Sep;
374(2079).
PMID: 27644972
We performed proteomics analysis on four skin and one muscle tissue samples taken from three ancient Egyptian mummies of the first intermediate period, approximately 4200 years old. The mummies were...
8.
Song X, Amirkhani A, Wu J, Pascovici D, Zaw T, Xavier D, et al.
Proteomics
. 2016 May;
16(15-16):2118-27.
PMID: 27233598
A standardized procedure for label-free nano-LC-SRM analysis of 32 high-medium abundance proteins from nondepleted human plasma was established and SRM data were acquired on 45 separate days for a control...
9.
Su S, Song X, Xavier D, Aquilina J
Proteins
. 2015 Aug;
83(10):1878-86.
PMID: 26238763
Low molecular weight peptides derived from the breakdown of crystallins have been reported in adult human lenses. The proliferation of these LMW peptides coincides with the earliest stages of cataract...
10.
Parker R, Vella L, Xavier D, Amirkhani A, Parker J, Cebon J, et al.
Front Oncol
. 2015 Jun;
5:95.
PMID: 26029660
The treatment of melanoma by targeted inhibition of the mutated kinase BRAF with small molecules only temporarily suppresses metastatic disease. In the face of chemical inhibition tumor plasticity, both innate...