David Kvaskoff
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Explore the profile of David Kvaskoff including associated specialties, affiliations and a list of published articles.
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43
Citations
475
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Recent Articles
1.
Klopp C, Zhang X, Campbell M, Kvaskoff D, Struwe M, Warren C, et al.
J Med Chem
. 2024 Oct;
67(20):18090-18097.
PMID: 39397364
-Hydroxyurea has been known since the 1960s as an antiproliferative drug and is used both in oncology and for treatment of hematological disorders such as sickle cell anemia where very...
2.
Metzler G, King R, Fernandez-Metzler C, Das A, Davis T, Bajrami B, et al.
Methods Mol Biol
. 2024 Oct;
2855:341-354.
PMID: 39354317
Bioactive lipid mediators derived from arachidonic acid constitute an attractive pool of metabolites that reflect cellular function and signaling, as well as potential biomarkers that may respond quantitatively to disease...
3.
Metzler G, Day L, King R, Fernandez-Metzler C, Das A, Davis T, et al.
Methods Mol Biol
. 2024 Oct;
2855:147-154.
PMID: 39354306
The analysis of prostaglandin urinary metabolites is valuable for assessing physiological processes and identifying disease biomarkers. These metabolites, derived from the breakdown of prostaglandins, offer a noninvasive means to gauge...
4.
Jones A, Bajrami B, Campbell M, Erzurumluoglu A, Guo Q, Chen H, et al.
Hepatol Commun
. 2024 Apr;
8(5).
PMID: 38619429
Background: Mutations in the gene MTARC1 (mitochondrial amidoxime-reducing component 1) protect carriers from metabolic dysfunction-associated steatohepatitis (MASH) and cirrhosis. MTARC1 encodes the mARC1 enzyme, which is localized to the mitochondria...
5.
Winter M, Simon R, Habe T, Ries R, Wang Y, Kvaskoff D, et al.
SLAS Discov
. 2023 Apr;
28(5):240-246.
PMID: 37031752
Acoustic droplet ejection-open port interface-mass spectrometry (ADE-OPI-MS) is a novel label-free analytical technique, promising to become a versatile readout for high-throughput screening (HTS) applications. The recent introduction of ADE-OPI-MS devices...
6.
Wallis T, Venkatesh B, Narayana V, Kvaskoff D, Ho A, Sullivan R, et al.
Nat Commun
. 2021 Jun;
12(1):3443.
PMID: 34103527
Polyunsaturated free fatty acids (FFAs) such as arachidonic acid, released by phospholipase activity on membrane phospholipids, have long been considered beneficial for learning and memory and are known modulators of...
7.
Wentrup C, Mirzaei M, Kvaskoff D, Taherpour A
J Org Chem
. 2021 Jun;
86(12):8286-8294.
PMID: 34077230
In the Dimroth rearrangement of heterocycles, often pyrimidines, an exocyclic and a ring substituent are interchanged. However, the term Dimroth rearrangement is frequently used even when there is no knowledge...
8.
Heath A, Hodge A, Ebeling P, Kvaskoff D, Eyles D, Giles G, et al.
J Steroid Biochem Mol Biol
. 2020 Feb;
198:105612.
PMID: 32007563
Vitamin D deficiency is associated with higher all-cause mortality, but associations with specific causes of death are unclear. We investigated the association between circulating 25-hydroxyvitamin D (25(OH)D) concentration and cause-specific...
9.
Lee B, Eyles D, Magnusson C, Newschaffer C, McGrath J, Kvaskoff D, et al.
Mol Psychiatry
. 2019 Nov;
26(5):1578-1588.
PMID: 31695167
Animal studies indicate that early life vitamin D is crucial for proper neurodevelopment. Few studies have examined whether maternal and neonatal vitamin D concentrations influence risk of autism spectrum disorders...
10.
Hambleton E, Jones V, Maegele I, Kvaskoff D, Sachsenheimer T, Guse A
Elife
. 2019 Jun;
8.
PMID: 31159921
Reef-building corals depend on intracellular dinoflagellate symbionts that provide nutrients. Besides sugars, the transfer of sterols is essential for corals and other sterol-auxotrophic cnidarians. Sterols are important cell components, and...