Keith Ashman
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Explore the profile of Keith Ashman including associated specialties, affiliations and a list of published articles.
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28
Citations
1540
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Recent Articles
1.
Humphries E, Xavier D, Ashman K, Hains P, Robinson P
J Proteome Res
. 2024 May;
23(7):2355-2366.
PMID: 38819404
High-throughput tissue proteomics has great potential in the advancement of precision medicine. Here, we investigated the combined sensitivity of trap-elute microflow liquid chromatography with a ZenoTOF for DIA proteomics and...
2.
Xavier D, Lucas N, Williams S, Koh J, Ashman K, Loudon C, et al.
Anal Chem
. 2024 Mar;
96(10):4093-4102.
PMID: 38427620
Proteomic analysis by mass spectrometry of small (≤2 mg) solid tissue samples from diverse formats requires high throughput and comprehensive proteome coverage. We developed a nearly universal, rapid, and robust...
3.
Poulos R, Hains P, Shah R, Lucas N, Xavier D, Manda S, et al.
Nat Commun
. 2020 Aug;
11(1):3793.
PMID: 32732981
Reproducible research is the bedrock of experimental science. To enable the deployment of large-scale proteomics, we assess the reproducibility of mass spectrometry (MS) over time and across instruments and develop...
4.
Sidjabat H, Gien J, Kvaskoff D, Ashman K, Vaswani K, Reed S, et al.
Sci Rep
. 2018 Mar;
8(1):3871.
PMID: 29497067
Antibiotic resistance associated with the clinically significant carbapenemases KPC, NDM and OXA-48 in Enterobacteriaceae is emerging as worldwide. In Australia, IMP-producing Enterobacteriaceae are the most prevalent carbapenemase-producing Enterobacteriaceae (CPE). Genomic...
5.
Vaswani K, Ashman K, Reed S, Salomon C, Sarker S, Arraztoa J, et al.
Biol Reprod
. 2015 Jun;
93(2):39.
PMID: 26108790
Inherent interindividual and intraindividual variation in the length of the menstrual cycle limits the accuracy of predicting days of peak fertility. To improve detection of days of peak fertility, a...
6.
Peiris H, Salomon C, Payton D, Ashman K, Vaswani K, Chan A, et al.
J Clin Endocrinol Metab
. 2014 Aug;
99(11):E2288-97.
PMID: 25093622
Context: Myostatin is a highly conserved secretory protein that negatively regulates muscle development by affecting both proliferation and differentiation of muscle cells. In human placentae the expression of myostatin is...
7.
Peiris H, Ashman K, Vaswani K, Kvaskoff D, Rice G, Mitchell M
J Proteome Res
. 2014 Jun;
13(8):3802-3809.
PMID: 24949862
Myostatin, a highly conserved secretory protein, negatively regulates muscle development, affecting both the proliferation and differentiation of muscle cells. Proteolytic processing of the myostatin precursor protein generates a myostatin pro-peptide...
8.
Navarro P, Trevisan-Herraz M, Bonzon-Kulichenko E, Nunez E, Martinez-Acedo P, Perez-Hernandez D, et al.
J Proteome Res
. 2014 Feb;
13(3):1234-47.
PMID: 24512137
The combination of stable isotope labeling (SIL) with mass spectrometry (MS) allows comparison of the abundance of thousands of proteins in complex mixtures. However, interpretation of the large data sets...
9.
Schonthaler H, Guinea-Viniegra J, Wculek S, Ruppen I, Ximenez-Embun P, Guio-Carrion A, et al.
Immunity
. 2013 Dec;
39(6):1171-81.
PMID: 24332034
Psoriasis is a common heterogeneous inflammatory skin disease with a complex pathophysiology and limited treatment options. Here we performed proteomic analyses of human psoriatic epidermis and found S100A8-S100A9, also called...
10.
Salomon C, Kobayashi M, Ashman K, Sobrevia L, Mitchell M, Rice G
PLoS One
. 2013 Nov;
8(11):e79636.
PMID: 24244532
Migration of extravillous trophoblasts (EVT) into decidua and myometrium is a critical process in the conversion of maternal spiral arterioles and establishing placenta perfusion. EVT migration is affected by cell-to-cell...