Karin A Jandeleit-Dahm
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Explore the profile of Karin A Jandeleit-Dahm including associated specialties, affiliations and a list of published articles.
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28
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1528
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Recent Articles
1.
Ouerd S, Idris-Khodja N, Trindade M, Ferreira N, Berillo O, Coelho S, et al.
Cardiovasc Res
. 2020 Jun;
117(4):1144-1153.
PMID: 32533834
Aims: NADPH oxidase (NOX) 1 but not NOX4-dependent oxidative stress plays a role in diabetic vascular disease, including atherosclerosis. Endothelin (ET)-1 has been implicated in diabetes-induced vascular complications. We showed...
2.
Deliyanti D, Alrashdi S, Touyz R, Kennedy C, Jha J, Cooper M, et al.
Hypertension
. 2020 Mar;
75(4):1091-1101.
PMID: 32114846
Hypertension is a risk factor for the vascular permeability and neovascularization that threatens vision in diabetic retinopathy. Excess reactive oxygen species derived from the Nox (NADPH oxidase) isoforms, Nox1 and...
3.
Watson A, Gould E, Penfold S, Lambert G, Pratama P, Dai A, et al.
Front Physiol
. 2019 May;
10:309.
PMID: 31040788
Patients with diabetic hypertensive nephropathy have accelerated disease progression. Diabetes and hypertension have both been associated with changes in renal catecholamines and reactive oxygen species. With a specific focus on...
4.
Pickering R, Tikellis C, Rosado C, Tsorotes D, Dimitropoulos A, Smith M, et al.
J Clin Invest
. 2018 Dec;
129(1):406-421.
PMID: 30530993
Activation of the type 1 angiotensin II receptor (AT1) triggers proinflammatory signaling through pathways independent of classical Gq signaling that regulate vascular homeostasis. Here, we report that the AT1 receptor...
5.
Mathew G, Sharma A, Pickering R, Rosado C, Lemarie J, Mudgal J, et al.
Free Radic Res
. 2018 Nov;
52(10):1140-1157.
PMID: 30422019
Inflammation is a protective immune response against invading pathogens, however, dysregulated inflammation is detrimental. As the complex inflammatory response involves multiple mediators, including the involvement of reactive oxygen species, concomitantly...
6.
Gill A, Gray S, Jandeleit-Dahm K, Watson A
Curr Diabetes Rev
. 2018 Apr;
15(5):349-356.
PMID: 29663893
Background: The sodium glucose co-transporter 2 (SGLT2) is primarily located within S1 of the renal proximal tubule being responsible for approximately 90% of glucose re-uptake in the kidney. Inhibition of...
7.
Chow B, Koulis C, Krishnaswamy P, Steckelings U, Unger T, Cooper M, et al.
Diabetologia
. 2016 May;
59(8):1778-90.
PMID: 27168137
Aims/hypothesis: Angiotensin II is well-recognised to be a key mediator in driving the pathological events of diabetes-associated atherosclerosis via signalling through its angiotensin II type 1 receptor (AT1R) subtype. However,...
8.
Allen T, Murphy A, Jandeleit-Dahm K
Diabetes
. 2015 Nov;
64(12):3981-3.
PMID: 26604171
No abstract available.
9.
Jha J, Thallas-Bonke V, Banal C, Gray S, Chow B, Ramm G, et al.
Diabetologia
. 2015 Oct;
59(2):379-89.
PMID: 26508318
Aims/hypothesis: Changes in podocyte morphology and function are associated with albuminuria and progression of diabetic nephropathy. NADPH oxidase 4 (NOX4) is the main source of reactive oxygen species (ROS) in...
10.
Ahrens I, Chen Y, Topcic D, Bode M, Haenel D, Hagemeyer C, et al.
Thromb Haemost
. 2015 Jul;
114(5):994-1003.
PMID: 26202300
High mobility group box 1 (HMGB1) acts as both a nuclear protein that regulates gene expression, as well as a pro-inflammatory alarmin that is released from necrotic or activated cells....